1 Result for "

Lipid N2-3L

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Lipid N2-3L" in MCE Product Catalog:

Cat. No.: HY-169478
CAS No.: 2924606-55-1
Target:  

Liposome

Research Areas:  

Cancer

Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that can be used to generate supramolecular lipid nanoparticles (SMLNPs) for mRNA delivery. Lipid nanoparticles formed by encapsulating a luciferase reporter gene with Lipid N2-3L were detected to accumulate in the lymph nodes of mice, indicating that they can effectively enter the mouse immune system. Lipid nanoparticles formed by encapsulating ovalbumin mRNA and the TLR7/8 agonist Resiquimod (HY-13740) with Lipid N2-3L were able to reduce tumor volume and increase survival in the MC-38-OVA mouse colon cancer model. Lipid N2-3L can be used in the research of drug delivery for cancer-related therapies .
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