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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
MEN 4
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "MEN 4" in MCE Product Catalog:
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5 Cited Publications
Synonyms: MK-677 free base; MK-0677 free base
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Ibutamoren (MK-677 free base; MK-0677 free base) is an orally active non-peptide growth hormone secretagogue receptor agonist. Ibutamoren activates signal cascades by mimicking endogenous ligands, triggers pulsatile release of growth hormone from the pituitary gland, and increases serum levels of IGF-1 and insulin-like growth factor-binding protein 3. Ibutamoren not only increases the frequency of growth hormone pulses in male individuals, but also promotes elevated bone formation markers in female individuals with postmenopausal osteoporosis. The combination of Ibutamoren with Alendronate sodium hydrate (HY-11101) significantly increases bone mineral density at the femoral neck. However, Ibutamoren may cause mild, reversible adverse reactions such as increased appetite, fluid retention, and elevated fasting blood glucose. Ibutamoren has been widely used in studies related to idiopathic growth hormone deficiency, sarcopenia, Alzheimer's disease, and osteoporosis .
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1 Cited Publications
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Menin-MLL inhibitor-22 (compound C20) is an orally active inhibitor of the interaction between menin and mixed lineage leukemia (MLL) (IC50=7 nM). Menin-MLL inhibitor-22 binds menin protein and inhibits cancer cell growth (MV4 cells, IC50=0.3 μM). Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome) .
Cat. No.: HY-P1031
CAS No.: 122063-01-8
Synonyms: MEN 10210
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Cat. No.: HY-P991665
Synonyms: OBT357NF; OBT357
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Cat. No.: HY-103304
CAS No.: 217438-17-0
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CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes .
Cat. No.: HY-W142023
CAS No.: 1047650-51-0
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Cat. No.: HY-W250654
CAS No.: 1628679-52-6
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PEG2-MeN-Boc is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-19395
CAS No.: 197506-04-0
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MEN-91507 is an orally activecysteinyl leukotriene receptor 1 (CysLTR1) receptor antagonist. MEN-91507 behaves as insurmountable antagonist of Leukotriene D4 (HY-113456)-induced calcium transients, with a pKb of 10.25. MEN-91507 can inhibit Leukotriene D4-induced bronchoconstriction and microvascular leakage in guinea-pigs. MEN-91507 can be used for the researches of inflammation, immunology .
Cat. No.: HY-151413A
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Cat. No.: HY-U00207
CAS No.: 214487-46-4
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MEN11467 is a selective and orally- effective peptidomimetic tachykinin NK1 receptor antagonist.
Cat. No.: HY-P1276
CAS No.: 135306-85-3
Synonyms: Neurokinin-2 receptor antagonist
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Cat. No.: HY-W369104
CAS No.: 1338075-62-9
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Boc-MeN-C5-OH is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-13745
CAS No.: 211100-13-9
Synonyms: MEN 10755
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Sabarubicin (MEN 10755) is a disaccharide analog of Doxorubicin (HY-15142A). Sabarubicin stimulates topoisomerase II-mediated DNA cleavage, induces DNA strand breaks and Apoptosis. Sabarubicin binds to and stabilizes telomeric G-quadruplex DNA. Sabarubicin is applicable to research related to ovarian tumors, breast cancer and lung cancer [4].
Cat. No.: HY-106277A
CAS No.: 869880-33-1
Synonyms: MEN16132
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Fasitibant chloride hydrochloride (MEN16132) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant chloride hydrochloride has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis .
Cat. No.: HY-123316
CAS No.: 136949-58-1
Synonyms: Xenetix
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Iobitridol (Xenetix) is a contrast agent with a higher incidence of adverse reactions in women than in men.
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Cat. No.: HY-14770
CAS No.: 522664-63-7
Synonyms: MEN 15596
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Ibodutant (MEN 15596) is a potent and selective tachykinin NK2 receptor antagonist with a pKi of 10.1.
Cat. No.: HY-P2439
CAS No.: 129781-07-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
