1 Result for "

MLN 8237 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MLN 8237 (Standard)" in MCE Product Catalog:

Cat. No.: HY-10971R
CAS No.: 1028486-01-2
Synonyms: MLN 8237 (Standard)
Research Areas:  

Cancer

Alisertib (Standard) is the analytical standard of Alisertib. This product is intended for research and analytical applications. Alisertib (MLN 8237) is an orally active and selective Aurora A kinase inhibitor (IC50=1.2 nM), which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib (MLN 8237) induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity .
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