1 Result for "

MRCK1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MRCK1" in MCE Product Catalog:

Cat. No.: HY-187203
Target:  

ROCK

Research Areas:  

Neurological Disease

RX-021 is a ROCK1 and ROCK2 inhibitor with IC50 values of 30.01 nM and 34.31 nM, respectively. RX-021 induces reversible morphological changes in human trabecular meshwork cells, maintains the survival of retinal ganglion cells, restores electroretinogram responses, and improves retinal histopathological changes. RX-021 achieves sustained reduction of intraocular pressure in a mouse model of ocular hypertension. RX-021 can be used for the research of glaucoma [1].
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