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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
NAD+ derivative
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "NAD+ derivative" in MCE Product Catalog:
24
24 Publications Verification
Cat. No.: HY-W015213
CAS No.: 6055-72-7
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2 Cited Publications
Synonyms: Riboflavine phosphate sodium; Riboflavin 5'-phosphate sodium; Riboflavine 5'-phosphate sodium
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1 Cited Publications
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KL1333, a derivative of β-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures .
Cat. No.: HY-W013713
CAS No.: 6184-17-4
Synonyms: Riboflavine phosphate sodium hydrate; Riboflavin 5'-phosphate sodium hydrate; Riboflavine 5'-phosphate sodium hydrate
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8-Br-NAD+ sodium is an NAD+ derivative that acts as a substrate for transfer to diversely modified ADP-ribosylated molecules .
Synonyms: Riboflavine phosphate; Riboflavin 5'-phosphate; Riboflavine 5'-phosphate
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Synonyms: Riboflavine phosphate sodium (Standard); Riboflavin 5'-phosphate sodium (Standard); Riboflavine 5'-phosphate sodium (Standard)
Synonyms: Tetradecyl nicotinate
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Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
Cat. No.: HY-161712
CAS No.: 2427862-70-0
IMPDH-IN-4 is a derivative of N-pyridinylthiophene carboxamid that exhibits activity against peripheral nerve sheath carcinoma cells. IMPDH-IN-4 is metabolized by NAMPT and NMNAT1 to an adenine dinucleotide (AD) derivative, which is an NAD analog and can inhibit inosine monophosphate dehydrogenase (IMPDH), leading to the accumulation of inosine monophosphate (IMP) in cells. IMPDH-IN-4 has good blood-brain barrier permeability and can be used in the study of central and peripheral nervous system cancers .
Cat. No.: HY-134301A
Synonyms: 8-Ethylthio-NAD+ sodium
8-ET-NAD+ (sodium) is the derivative of NAD+. 8-ET-NAD+ (sodium) can be used in screening of PARP1 gatekeeper mutations. 8-ET-NAD+ (sodium) can be studied in research on cancer .
Cat. No.: HY-134280
CAS No.: 477782-33-5
Synonyms: Nicotinamide 8-Br-hypoxanthine dinucleotide
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8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog .
Cat. No.: HY-133027R
CAS No.: 273203-62-6
Synonyms: Tetradecyl nicotinate (Standard)
Research Areas:
Myristyl nicotinate (Standard) is the analytical standard of Myristyl nicotinate. This product is intended for research and analytical applications. Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
Cat. No.: HY-W015213S
Cat. No.: HY-W721166
Synonyms: Riboflavine phosphate-d3 sodium; Riboflavin 5'-phosphate-d3 sodium; Riboflavine 5'-phosphate-d3 sodium
Cat. No.: HY-134270A
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8-Br-7-CH-NAD+ sodium is a derivative of NAD+ (HY-B0445). 8-Br-7-CH-NAD+ sodium can be used to synthesize an antagonist for TRPM2 .
Cat. No.: HY-134349A
Synonyms: 8-Piperidino-NAD+ sodium
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8-PIP-NAD+ (sodium) (8-Piperidino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-PIP-NAD+ (sodium) can be used in the determination of poly(ADP-ribose) polymerase (PARP) target proteins. 8-PIP-NAD+ (sodium) is a synthetic intermediate in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
Cat. No.: HY-134305A
Synonyms: 8-Methylamino-NAD+ sodium
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8-MA-NAD+ (sodium) (8-Methylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-MA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations. 8-MA-NAD+ (sodium) can be used in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
Cat. No.: HY-134300A
Synonyms: 8-Dimethylamino-NAD+ sodium
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8-DMA-NAD+ (sodium) (8-Dimethylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-DMA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations .
Cat. No.: HY-157906
CAS No.: 47775-00-8
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ADP-β-D-ribofuranose is a nucleotide derivative composed of ADP and a ribose unit. ADP-β-D-ribofuranose can be produced by NAD + catalysis .
Cat. No.: HY-171416
CAS No.: 1955527-32-8
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LCD36, a derivative of nicotinamide adenine dinucleotide (NAD), can be used for synthesis of PARP-1 tracers for positron emission tomography (PET) imaging of the enzyme activity of PARP-1 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
