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  4. 8-Br-NAD+ sodium

8-Br-NAD+ sodium is an NAD+ derivative that acts as a substrate for transfer to diversely modified ADP-ribosylated molecules.

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8-Br-NAD+ sodium Chemical Structure

8-Br-NAD+ sodium Chemical Structure

CAS No. : 2022926-16-3

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Based on 1 publication(s) in Google Scholar

8-Br-NAD+ sodium Related Antibodies

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Description

8-Br-NAD+ sodium is an NAD+ derivative that acts as a substrate for transfer to diversely modified ADP-ribosylated molecules[1].

Molecular Weight

764.30

Formula

C21H25BrN7NaO14P2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]([C@H]([C@@](N1C(Br)=NC2=C(N)N=CN=C21)([H])O3)O)[C@H]3COP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@@]([N+]5=CC=CC(C(N)=O)=C5)([H])O4)([O-])=O)(O[Na])=O
Shipping

Shipping with dry ice.
Storage

-80°C
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (65.42 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3084 mL 6.5419 mL 13.0839 mL
5 mM 0.2617 mL 1.3084 mL 2.6168 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥97.0%

COA (249 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.3084 mL 6.5419 mL 13.0839 mL 32.7097 mL
5 mM 0.2617 mL 1.3084 mL 2.6168 mL 6.5419 mL
10 mM 0.1308 mL 0.6542 mL 1.3084 mL 3.2710 mL
15 mM 0.0872 mL 0.4361 mL 0.8723 mL 2.1806 mL
20 mM 0.0654 mL 0.3271 mL 0.6542 mL 1.6355 mL
25 mM 0.0523 mL 0.2617 mL 0.5234 mL 1.3084 mL
30 mM 0.0436 mL 0.2181 mL 0.4361 mL 1.0903 mL
40 mM 0.0327 mL 0.1635 mL 0.3271 mL 0.8177 mL
50 mM 0.0262 mL 0.1308 mL 0.2617 mL 0.6542 mL
60 mM 0.0218 mL 0.1090 mL 0.2181 mL 0.5452 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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8-Br-NAD+ sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-Br-NAD+2022926-16-3OthersNAD+derivativeADP-ribosylatedInhibitorinhibitorinhibit

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