2. Search Result
Search Result
Results for "

NAD derivative

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

2

Biochemical Assay Reagents

6

Natural
Products

2

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0964
    Riboflavin phosphate sodium
    2 Publications Verification

    Riboflavine phosphate sodium; Riboflavin 5'-phosphate sodium; Riboflavine 5'-phosphate sodium

    		 Endogenous Metabolite Others
    Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism . Riboflavine phosphate sodium is a very effective NAD +-recycling agent .
    Riboflavin phosphate sodium
  • HY-128895
    KL1333
    1 Publications Verification

    		 Quinone Reductase Mitochondrial Metabolism Metabolic Disease
    KL1333, a derivative of β-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures .
    KL1333
  • HY-W013713
    Riboflavin phosphate sodium hydrate

    Riboflavine phosphate sodium hydrate; Riboflavin 5'-phosphate sodium hydrate; Riboflavine 5'-phosphate sodium hydrate

    		 Endogenous Metabolite Others
    Riboflavine phosphate sodium hydrate (Riboflavine 5'-phosphate sodium hydrate) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavine phosphate sodium hydrate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism . Riboflavine phosphate sodium hydrate is a very effective NAD +-recycling agent .
    Riboflavin phosphate sodium hydrate
  • HY-W722277A
    LCC-12 formate

    		Interleukin Related NADH Dehydrogenase TNF Receptor JAK STAT IRAK Inflammation/Immunology
    LCC-12 (formate) is a copper (II) chelator and a derivative of the biguanide metformin (HY-B0627). LCC-12 (formate) reduces its hydrogen peroxide-dependent oxidation of NADH to NAD+. LCC-12 (formate) reduces IL-1β, IL-2, IL-6, IL-8, and TNF-α levels, as well as JAK2, STAT2, and IL-1 receptor-associated kinase 4 (IRAK4) levels in primary human cytokine-activated monocyte-derived macrophages (MDMs). LCC-12 (formate) reduces the number of CD80+ and CD86+ cytokine-activated MDMs. LCC-12 LCC-12 (formate) improves survival in a mouse model of sepsis induced by LPS or cecal ligation and puncture .
    LCC-12 formate
  • HY-134279
    8-Br-NAD+ sodium

    		Calcium Channel Others
    8-Br-NAD+ sodium is an NAD+ derivative that acts as a substrate for transfer to diversely modified ADP-ribosylated molecules .
    8-Br-NAD+ sodium
  • HY-B0964A
    Riboflavin phosphate

    Riboflavine phosphate; Riboflavin 5'-phosphate; Riboflavine 5'-phosphate

    		 Endogenous Metabolite Metabolic Disease
    Riboflavine phosphate is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism . Riboflavine phosphate is a very effective NAD +-recycling agent .
    Riboflavin phosphate
  • HY-B0964R
    Riboflavin phosphate sodium (Standard)

    Riboflavine phosphate sodium (Standard); Riboflavin 5'-phosphate sodium (Standard); Riboflavine 5'-phosphate sodium (Standard)

    		 Reference Standards Endogenous Metabolite Others
    Riboflavin phosphate (sodium) (Standard) is the analytical standard of Riboflavin phosphate (sodium). This product is intended for research and analytical applications. Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism . Riboflavine phosphate sodium is a very effective NAD+-recycling agent .
    Riboflavin phosphate sodium (Standard)
  • HY-133027
    Myristyl nicotinate

    Tetradecyl nicotinate

    		 Biochemical Assay Reagents Cancer
    Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
    Myristyl nicotinate
  • HY-W015213
    Adenine monohydrochloride hemihydrate
    20+ Cited Publications

    		 Endogenous Metabolite DNA/RNA Synthesis Metabolic Disease
    Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
    Adenine monohydrochloride hemihydrate
  • HY-161712
    IMPDH-IN-4

    		IMPDH Cancer
    IMPDH-IN-4 is a derivative of N-pyridinylthiophene carboxamid that exhibits activity against peripheral nerve sheath carcinoma cells. IMPDH-IN-4 is metabolized by NAMPT and NMNAT1 to an adenine dinucleotide (AD) derivative, which is an NAD analog and can inhibit inosine monophosphate dehydrogenase (IMPDH), leading to the accumulation of inosine monophosphate (IMP) in cells. IMPDH-IN-4 has good blood-brain barrier permeability and can be used in the study of central and peripheral nervous system cancers .
    IMPDH-IN-4
  • HY-131829
    N6-(2-Aminoethyl)-NAD+

    6-AE-NAD+

    		 Biochemical Assay Reagents Others
    N6-(2-Aminoethyl)-NAD+ (6-AE-NAD+) is a NAD+ derivative commonly used in affinity chromatography. N6-(2-Aminoethyl)-NAD+ can be covalently linked to a PQQ (pyrroloquinoline quinone) (HY-100196) monolayer on an electrode surface for immobilizing NAD+-dependent enzymes such as lactate dehydrogenase (LDH) .
    N6-(2-Aminoethyl)-NAD+
  • HY-131485A
    3-Acetylpyridine adenine dinucleotide, 95%

    3-APAD, 95%; 3-Acetylpyridine NAD, 95%

    		 Lactate Dehydrogenase Metabolic Disease
    3-Acetylpyridine adenine dinucleotide, 95% (3-APAD, 95%)is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 95% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite .
    3-Acetylpyridine adenine dinucleotide, 95%
  • HY-134301A
    8-ET-NAD+ sodium

    8-Ethylthio-NAD+ sodium

    		 PARP Cancer
    8-ET-NAD+ (sodium) is the derivative of NAD+. 8-ET-NAD+ (sodium) can be used in screening of PARP1 gatekeeper mutations. 8-ET-NAD+ (sodium) can be studied in research on cancer .
    8-ET-NAD+ sodium
  • HY-134280
    8-Br-NHD+

    Nicotinamide 8-Br-hypoxanthine dinucleotide

    		 Drug Derivative Others
    8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog .
    8-Br-NHD+
  • HY-133027R
    Myristyl nicotinate (Standard)

    Tetradecyl nicotinate (Standard)

    		 Biochemical Assay Reagents Reference Standards Cancer
    Myristyl nicotinate (Standard) is the analytical standard of Myristyl nicotinate. This product is intended for research and analytical applications. Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
    Myristyl nicotinate (Standard)
  • HY-W015213S
    Adenine monohydrochloride hemihydrate-15N5

    		Isotope-Labeled Compounds Endogenous Metabolite DNA/RNA Synthesis Metabolic Disease
    Adenine monohydrochloride hemihydrate- 15N5 is the 15N labeled Adenine monohydrochloride hemihydrate (HY-W015213). Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
    Adenine monohydrochloride hemihydrate-15N5
  • HY-W721166
    Riboflavin phosphate-d3 sodium

    Riboflavine phosphate-d3 sodium; Riboflavin 5'-phosphate-d3 sodium; Riboflavine 5'-phosphate-d3 sodium

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Riboflavin phosphate-d3 sodium (Riboflavine phosphate-d3 sodium; Riboflavin 5'-phosphate-d3 sodium; Riboflavine 5'-phosphate-d3 sodium) is the deuterium labeled Riboflavin phosphate sodium (HY-B0964). Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism . Riboflavine phosphate sodium is a very effective NAD+-recycling agent .
    Riboflavin phosphate-d3 sodium
  • HY-134349A
    8-PIP-NAD+ sodium

    8-Piperidino-NAD+ sodium

    		 Endogenous Metabolite Others
    8-PIP-NAD+ (sodium) (8-Piperidino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-PIP-NAD+ (sodium) can be used in the determination of poly(ADP-ribose) polymerase (PARP) target proteins. 8-PIP-NAD+ (sodium) is a synthetic intermediate in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
    8-PIP-NAD+ sodium
  • HY-134305A
    8-MA-NAD+ sodium

    8-Methylamino-NAD+ sodium

    		 Endogenous Metabolite Others
    8-MA-NAD+ (sodium) (8-Methylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-MA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations. 8-MA-NAD+ (sodium) can be used in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
    8-MA-NAD+ sodium
  • HY-131829A
    N6-(2-Aminoethyl)-NAD+ sodium

    6-AE-NAD+ sodium

    		 Biochemical Assay Reagents Others
    N6-(2-Aminoethyl)-NAD+ (6-AE-NAD+) sodium is a NAD+ derivative commonly used in affinity chromatography. N6-(2-Aminoethyl)-NAD+ sodium can be covalently linked to a PQQ (pyrroloquinoline quinone) (HY-100196) monolayer on an electrode surface for immobilizing NAD+-dependent enzymes such as lactate dehydrogenase (LDH) .
    N6-(2-Aminoethyl)-NAD+ sodium
  • HY-134300A
    8-DMA-NAD+ sodium

    8-Dimethylamino-NAD+ sodium

    		 Endogenous Metabolite Others
    8-DMA-NAD+ (sodium) (8-Dimethylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-DMA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations .
    8-DMA-NAD+ sodium
  • HY-134270A
    8-Br-7-CH-NAD+ sodium

    		Drug Derivative Metabolic Disease
    8-Br-7-CH-NAD+ sodium is a derivative of NAD+ (HY-B0445). 8-Br-7-CH-NAD+ sodium can be used to synthesize an antagonist for TRPM2 .
    8-Br-7-CH-NAD+ sodium
  • HY-171416
    LCD36

    		Drug Derivative Others
    LCD36, a derivative of nicotinamide adenine dinucleotide (NAD), can be used for synthesis of PARP-1 tracers for positron emission tomography (PET) imaging of the enzyme activity of PARP-1 .
    LCD36
  • HY-E71187
    13,14-Dehydro-15-oxoprostaglandin 13-reductase

    		Biochemical Assay Reagents Others
    13,14-Dehydro-15-oxoprostaglandin 13-reductase (EC 1.3.1.48) reduces 13,14-Dehydro-15-oxoprostaglandins to 13,14-dihydro derivatives. 13,14-Dehydro-15-oxoprostaglandin 13-reductase (EC 1.3.1.48) is specific for NAD+.
    13,14-Dehydro-15-oxoprostaglandin 13-reductase
  • HY-179523
    Carba1

    		Drug Derivative NAMPT Microtubule/Tubulin Neurological Disease Cancer
    Carba1 is a bifunctional Carbazole (HY-D0204) derivative that activates nicotinamide phosphoribosyltransferase (NAMPT) and enhances NAD biosynthesis. Carba1 binds to colchicine site of tubulin, enhancing the anti-tumor effect of various chemotherapy drugs, such as Paclitaxel (HY-B0015). Carba1 exerts neuroprotective effect and can regulate cell energy metabolism. Carba1 can be used for the researches of cancer and chemotherapy-induced peripheral neuropathy (CIPN) .
    Carba1
  • HY-W015213R
    Adenine monohydrochloride hemihydrate (Standard)

    		Endogenous Metabolite Reference Standards DNA/RNA Synthesis Metabolic Disease
    Adenine monohydrochloride hemihydrate (Standard) is the analytical standard of Adenine monohydrochloride hemihydrate (HY-W015213). This product is intended for research and analytical applications. Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
    Adenine monohydrochloride hemihydrate (Standard)
  • HY-181124
    Idebenone-SS-20

    Idebenone-2S-FrFK-NH2

    		 Drug Derivative Reactive Oxygen Species (ROS) Mitochondrial Metabolism Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Idebenone-SS-20 (Idebenone-2S-FrFK-NH2) is a Idebenone (HY-N0303) derivative conjugated to the mitochondria-targeting peptide SS-20. Idebenone-SS-20 shows neuroprotective and anti-inflammatory effects. Idebenone-SS-20 can preserve mitochondrial membrane potential, enhance ATP production, reduce ROS accumulation, maintain mitochondrial morphology and elevate NAD+/NADH ratio. Idebenone-SS-20 confers robust neuroprotection in a murine model of transient middle cerebral artery occlusion. Idebenone-SS-20 can be used for the research of cerebral .
    Idebenone-SS-20

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: