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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
NR-HOCl-TFMU
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "NR-HOCl-TFMU" in MCE Product Catalog:
Cat. No.: HY-D3443
Target:
Research Areas:
NR-HOCl-TFMU is a HOCl-gated phosphonite fluorescent probe based on the Nebraska Red scaffold. NR-HOCl-TFMU undergoes HOCl-triggered oxidative ring-opening of the spirocyclic thioether and phosphonite hydrolysis to synchronously release the near-infrared reporter group NR666-MSA (Ex 666 nm/Em 698 nm) and the cargo TFMU (Ex 405 nm/Em 510 nm) . NR-HOCl-TFMU enables HOCl-selective fluorescence imaging and cargo release monitoring in vitro, in live cells and in vivo, and exerts gated selective cytotoxicity in HOCl-positive cells. NR-HOCl-TFMU can be used for studies related to acute myeloid leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
