1 Result for "

NS 0011

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NS 0011" in MCE Product Catalog:

Art. -Nr.: HY-183235
CAS. Nr.: 1076234-33-7
Target:  

CDK

Forschungsgebiete:  

Cancer

NS-0011 is a CDK5 inhibitor with a Kd value of 16 μM. NS-0011 binds to the nuclear export signal domain of CDK5, disrupts its interaction with CRM-1 and increases the accumulation of CDK5 in the nucleus. NS-0011 inhibits the proliferation of gastric cancer cells. NS-0011 suppresses the occurrence of gastric cancer xenograft tumors. NS-0011 is applicable to gastric cancer-related research .
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