25 Results for "

Olfactory Receptor

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "Olfactory Receptor" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-116144
CAS No.: 119515-38-7
Purity:  98.00%
Synonyms: Lcaridin
Research Areas:  

Infection

Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial, anticandidal and antifungal properties .
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2
2 Cited Publications
Cat. No.: HY-135190
CAS No.: 469-61-4
Purity:  ≥98.0%
Synonyms: α-cedrene
(-)-Cedrene (α-cedrene) is a major constituent that can be found in essential oils. (-)-Cedrene (α-cedrene) is a natural, orally active ligand of mouse olfactory receptor 23, which induces skeletal muscle hypertrophy in mice. (-)-Cedrene exhibits trypanocidal (Trypanosoma b. brucei) (IC50 = 4.07 μg/mL). (-)-Cedrene is antileukemic in vitro (IC50 = 22.2 μg/mL). (-)-Cedrene has antimicrobial activity against anaerobic bacteria and yeast. (-)-Cedrene exhibits anti-obesity activity .
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1
1 Cited Publications
Cat. No.: HY-125751
CAS No.: 1434515-70-4
Purity:  99.53%
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

UCSF924, a chemical probe, is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has no off-target effects on more than 320 non-olfactory GPCRs. UCSF924 can be used for research in the field of neuropsychiatric diseases .
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Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-N8847
CAS No.: 127-41-3
Synonyms: alpha-Ionone
α-Ionone (alpha-Ionone) is an activator of the olfactory receptor OR10A6. α-Ionone induces apoptosis by activating OR10A6 and increasing the phosphorylation of the LATS-YAP-TAZ signaling axis in the Hippo pathway. α-Ionone can inhibit tumor formation both in vivo and in vitro .
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Cat. No.: HY-139783
CAS No.: 65113-99-7
Purity:  ≥98.0%
Research Areas:  

Others

3-Campholenyl-2-butanol, a synthetic sandalwood odorant, is a selective olfactory receptor OR2AT4 agonist. 3-Campholenyl-2-butanol prolongs human hair growth ex vivo by decreasing apoptosis and increasing production of the anagen-prolonging growth factor IGF-1 in the outer root sheath (ORS) .
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Cat. No.: HY-125982
CAS No.: 525582-84-7
Purity:  ≥98.0%
Target:  

Insecticide

Research Areas:  

Others

VUAA1 is an insect odorant co-receptor (Orco) agonist. VUAA1 activates both heteromeric and homomeric Orco-containing channels. VUAA1 can disrupt the destructive behaviors of nuisance insects. VUAA1 can be used for insect olfactory research .
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Cat. No.: HY-N7707
CAS No.: 28219-61-6
Research Areas:  

Cancer

Sandacanol is a specific agonist of olfactory receptor (OR10H1). Sandacanol induces cell cycle arrest and some apoptosis in bladder cancer cells .
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Cat. No.: HY-116144R
CAS No.: 119515-38-7
Synonyms: Lcaridin (Standard)
Research Areas:  

Infection

Picaridin (Standard) is the analytical standard of Picaridin. This product is intended for research and analytical applications. Picaridin (Lcaridin) is a broad spectrum arthropod repellent. The repellent and deterrent activities of Picaridin involve olfactory sensing in mosquitoes, and ticks, via their interactions with odorant receptor proteins .
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Cat. No.: HY-118967
CAS No.: 663212-40-6
Synonyms: VU0183254
Target:  

HCN Channel

Research Areas:  

Others

VUANT1 (VU0183254) is an allosteric antagonist of insect odorant receptor ion channels, which has the activity of inhibiting insect odorant receptor signaling. VUANT1 can inhibit the activation of insect odorant receptors through allosteric regulation, which is important for the study of the molecular mechanism of insect olfactory signaling. Although it may be of limited use in insect control programs, it can be used as a pharmacological tool to study related mechanisms.
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Cat. No.: HY-N14827
CAS No.: 151466-15-8
Synonyms: SM-216289
Target:  

Drug Derivative

Xanthofulvin (SM-216289) is an inhibitor of semaphorin 3A. Xanthofulvin blocks its binding to receptors, inhibits growth cone collapse, and accelerates olfactory nerve regeneration in rats in vivo. Xanthofulvin can be used in studies related to traumatic neuronal injury .
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Cat. No.: HY-W097929
CAS No.: 87-40-1
Synonyms: 2,4,6-Trichloroanisole
Tyrene (2,4,6-Trichloroanisole) is an off-flavor compound, cyclic nucleotide-gated (CNG) channel inhibitor, and olfactory transduction attenuator. Tyrene is formed by microbial O-methylation of 2,4,6-trichlorophenol. Tyrene inhibits channel activity in olfactory receptor cells by partitioning into the plasma membrane lipid bilayer, and also suppresses odorant- and cAMP-induced currents in individual olfactory receptor cells. Tyrene causes cork taint in wine. Tyrene also produces off-flavors in potato chips, dried fruits, coffee, and drinking water .
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Cat. No.: HY-W109323
CAS No.: 38363-29-0
Synonyms: (E)-8-Dodecen-1-yl acetate; trans-8-Dodecenyl acetate
Target:  

Olfactory Receptor

Research Areas:  

Infection

(E)-8-Dodecenyl ((E)-8-Dodecen-1-yl; trans-8-Dodecenyl) acetate is a sex pheromone targeting the olfactory receptors of male Gymnandrosoma aurantianum moths. acting as an agonist. (E)-8-Dodecenyl acetate is promising for research of agricultural pests .
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Cat. No.: HY-W822786
CAS No.: 144625-67-2
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

GR125487 is a highly selective and potent 5-HT4 receptor (5-HT4 receptor) antagonist with a Kd value of 0.1 nM. GR125487 has an extremely low affinity for 5-HT3 receptors (Kd > 1 μM). GR125487 completely antagonizes the memory-promoting effect of BIMU1, and its administration alone has no significant effect on basic social memory. GR125487 can be used for the study of social olfactory memory .
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Cat. No.: HY-145788
CAS No.: 147159-38-4
Target:  

Olfactory Receptor

Research Areas:  

Cancer

5-Cyclopropylpentanal is an olfactory receptor agonist. 5-Cyclopropylpentanal enhance OR-I7 activation with an EC50 of 0.3 μM .
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Cat. No.: HY-W021008S
Synonyms: Dimethylhydroxyfuranone-d2
Sotolone-d2 (Dimethylhydroxyfuranone-d2) is deuterated labeled Sotolone. Sotolone is an activator of the human olfactory receptor OR8D1. Sotolone activates the human olfactory receptor OR8D1, with EC50 values of 84.98 μM and 167.2 μM for its S-enantiomer and R-enantiomer, respectively. Sotolone has unique aroma profiles: (R)-sotolone exhibits smoky, burnt, herbal and grassy notes; (S)-sotolone presents sweet, milky, sour and nutty notes. Sotolone also acts as an antifungal agent, showing moderate inhibitory activity against Magnaporthe oryzae in vitro .
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Cat. No.: HY-110024A
CAS No.: 135722-25-7
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

S-14506 hydrochloride is a potent 5-HT1A agonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent .
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Cat. No.: HY-171328
CAS No.: 1076189-55-3
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

RG-15 is the orally active antagonist for dopamine receptor that exhibits goof affinity to human D2 receptor and human D3 receptor with pKi of 8.23 and 10.49. RG-15 inhibits dopamine-stimulated [ 35S]GTPγS binding with IC50 of 21.2 nM (rat striatal membranes), 36.7 nM (mouse A9 cells expressing human D2L receptors) and 7.2 nM (CHO cells expressing human D3 receptors). RG-15 increases the turnover and biosynthesis of dopamine in mouse striatum and olfactory bulb, exhibiting antipsychotic activity .
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Cat. No.: HY-N8847R
CAS No.: 127-41-3
Synonyms: alpha-Ionone (Standard)
α-Ionone (Standard) is the analytical standard of α-Ionone. This product is intended for research and analytical applications. α-Ionone (alpha-Ionone) is an activator of the olfactory receptor OR10A6. α-Ionone induces apoptosis by activating OR10A6 and increasing the phosphorylation of the LATS-YAP-TAZ signaling axis in the Hippo pathway. α-Ionone can inhibit tumor formation both in vivo and in vitro .
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Cat. No.: HY-110024
CAS No.: 286369-38-8
Purity:  99.92%
Research Areas:  

Neurological Disease

S-14506 hydrochloride is a potent 5-HT1A agonist, as well as 5-HT2A/2C antagonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent .
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