151466-15-8
151466-15-8
Chemical Structure
Xanthofulvin
Synonym(s): SM-216289
- CAS No.: 151466-15-8
- Formula:C28H18O14
- Molecular Weight:578.43
InChIKey: VZJACTNXARYXEM-NHDPSOOVSA-N
SMILES: O=C(C(C(O)=C(C=C1OC2=C3C=C(C(C)=C2C(C)=O)/C(O)=C4C(C5=C(C(O)=O)C(O)=C(O)C=C5OC/4)=O)O)=C1C3=O)O
Biological Activity: Xanthofulvin (SM-216289) is an inhibitor of semaphorin 3A. Xanthofulvin blocks its binding to receptors, inhibits growth cone collapse, and accelerates olfactory nerve regeneration in rats in vivo. Xanthofulvin can be used in studies related to traumatic neuronal injury[1][2].
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Xanthofulvin | Xanthofulvin (SM-216289) is an inhibitor of semaphorin 3A. Xanthofulvin blocks its binding to receptors, inhibits growth cone collapse, and accelerates olfactory nerve regeneration in rats in vivo. Xanthofulvin can be used in studies related to traumatic neuronal injury. | |||||||||||||||||||||
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References
- [1]. Kumagai K, et al. Xanthofulvin, a novel semaphorin inhibitor produced by a strain of Penicillium. J Antibiot (Tokyo). 2003 Jul;56(7):610-6. [Content Brief]
- [2]. Kikuchi K, et al. In vitro and in vivo characterization of a novel semaphorin 3A inhibitor, SM-216289 or xanthofulvin. J Biol Chem. 2003;278(44):42985-42991. [Content Brief]
Keywords
