144625-67-2
Chemical Structure
GR125487
- CAS No.: 144625-67-2
- Formula:C19H26FN3O5S
- Molecular Weight:427.49
InChIKey: SSPCCAYAIDNNJX-UHFFFAOYSA-N
SMILES: O=C(OCC1CCN(CCNS(=O)(=O)C)CC1)C2=C(OC)NC=3C=CC(F)=CC32
Biological Activity:
GR125487 is a highly selective and potent 5-HT4 receptor (5-HT4 receptor) antagonist with a Kd value of 0.1 nM. GR125487 has an extremely low affinity for 5-HT3 receptors (Kd > 1 μM). GR125487 completely antagonizes the memory-promoting effect of BIMU1, and its administration alone has no significant effect on basic social memory. GR125487 can be used for the study of social olfactory memory[1].
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GR125487 | GR125487 is a highly selective and potent 5-HT4 receptor (5-HT4 receptor) antagonist with a Kd value of 0.1 nM. GR125487 has an extremely low affinity for 5-HT3 receptors (Kd > 1 μM). GR125487 completely antagonizes the memory-promoting effect of BIMU1, and its administration alone has no significant effect on basic social memory. GR125487 can be used for the study of social olfactory memory. |
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Keywords
