17 Results for "

Omeprazole D3

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Omeprazole D3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-B0113S
CAS No.: 922731-01-9
Synonyms: H 16868-d3
Omeprazole-d3 (H 16868-d3) is deuterium labeled Omeprazole. Omeprazole (H 16868) is an orally active H +,K +-ATPase inhibitor and a proton pump inhibitor. Omeprazole competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole aslo has neuroprotective and antibacterial effects .
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Cat. No.: HY-B0113S3
CAS No.: 1261395-28-1
Synonyms: H 16868-13C,d3
Omeprazole- 13C,d3 is a 13C-labeled and deuterium labeled Omeprazole. Omeprazole (H 16868) is an orally active H +,K +-ATPase inhibitor and a proton pump inhibitor. Omeprazole competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole aslo has neuroprotective and antibacterial effects .
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Cat. No.: HY-17021S1
Synonyms: (S)-Omeprazole-d3; (-)-Omeprazole-d3
Esomeprazole-d3 is deuterium labeled Esomeprazole. Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research .
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Cat. No.: HY-126857S
CAS No.: 2748479-83-4
Pureté:  98.27%
5-Hydroxy Omeprazole-d3 is deuterium labeled 5-Hydroxyomeprazole.
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Cat. No.: HY-138199S
CAS No.: 2740875-18-5
Omeprazole sulfone N-Oxide- 13C,d3 is the 13C,d3 Omeprazole sulfone N-Oxide (HY-138199). Omeprazole sulfone N-Oxide is an Omeprazole (HY-B0113) analog with binding affinity to Nilaparvata lugens choline acetyltransferase (ChAT) .
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Cat. No.: HY-W131494S
(N)-Methyl omeprazole-d3 is the deuterium labeled (N)-Methyl omeprazole .
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Cat. No.: HY-138199S1
CAS No.: 2748468-58-6
Omeprazole sulfone N-Oxide-d3 is the d3-labeled Omeprazole sulfone N-Oxide (HY-138199). Omeprazole sulfone N-Oxide is an Omeprazole (HY-B0113) analog with binding affinity to Nilaparvata lugens choline acetyltransferase (ChAT) .
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Cat. No.: HY-141776S
CAS No.: 922730-98-1
Pureté:  99.79%
Synonyms: Ufiprazole-d3
Omeprazole sulfide-d3 is the deuterium labeled Omeprazole sulfide. Omeprazole metabolite Omeprazole sulfide (Ufiprazole) is a metabolite of Omeprazole, which is a proton pump inhibitor.
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Cat. No.: HY-135111S
CAS No.: 1794759-05-9
4-Desmethoxy Omeprazole-d3 is the deuterium labeled 4-Desmethoxy Omeprazole. 4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Kiof 2 to 6 μM . Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria .
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Cat. No.: HY-17021S
Synonyms: (S)-Omeprazole-D3 sodium; (-)-Omeprazole-D3 sodium
Esomeprazole-d3 (sodium) is the deuterium labeled Esomeprazole. Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research .
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Cat. No.: HY-17021S2
Synonyms: (S)-Omeprazole-D3 potassium; (-)-Omeprazole-D3 potassium
Esomeprazole-d3 potassium is deuterated labeled Esomeprazole (HY-17021). Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H +, K +-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research .
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Cat. No.: HY-B0113S4
Synonyms: H 16868-D3 sodium
Omeprazole-d3 sodium is deuterated labeled Omeprazole (HY-B0113). Omeprazole sodium (H 16868) is an orally active H +,K +-ATPase inhibitor and a proton pump inhibitor. Omeprazole sodium competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole sodium inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole sodium inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole sodium alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole sodium aslo has neuroprotective and antibacterial effects .
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Cat. No.: HY-G0007S
CAS No.: 2749628-17-7
Synonyms: Omeprazole sulfone-d3; Omeprazole sulphone-d3
Omeprazole sulfone-d3 is the deuterium labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
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Cat. No.: HY-B0113S2
CAS No.: 1189891-71-1
Synonyms: Omeprazole sulphone (methoxy-d3)
Omeprazole sulfone (methoxy-d3) is the deuterium labeled Omeprazole sulfone. Omeprazole sulfone (H 16868) is an orally active H +,K +-ATPase inhibitor and a proton pump inhibitor. Omeprazole sulfone competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole sulfone inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole sulfone inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole sulfone alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole sulfone aslo has neuroprotective and antibacterial effects .
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Cat. No.: HY-B0113S1
CAS No.: 934293-92-2
Synonyms: H 16868-d3-1
Omeprazole-d3-1 is the deuterium labeled Omeprazole. Omeprazole-1 (H 16868) is an orally active H +,K +-ATPase inhibitor and a proton pump inhibitor. Omeprazole-1 competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole-1 inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole-1 inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole-1 alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole-1 aslo has neuroprotective and antibacterial effects .
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Cat. No.: HY-G0007S1
CAS No.: 1261393-28-5
Synonyms: Omeprazole sulfone-13C,d3; Omeprazole sulphone-13C,d3
Omeprazole sulfone- 13C,d3 is the deuterium and 13C labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
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Cat. No.: HY-141731S
CAS No.: 1794938-78-5
Synonyms: 4-Desmethoxy Omeprazole sulfide-d3
4-Desmethoxy Omeprazole-d3 sulfide is the deuterium labeled 4-Desmethoxy Omeprazole sulfide .
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