1 Result for "

Oxaprozin-d10

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Oxaprozin-d10" in MCE Product Catalog:

Cat. No.: HY-W709448
Synonyms: Oxaprozinum-d10; Wy21743-d10
Oxaprozin-d10 (Oxaprozinum-d10; Wy21743-d10) is the deuterium labeled Oxaprozin (HY-B0808). Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
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