1 Result for "

PARP1-IN-40

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PARP1-IN-40" in MCE Product Catalog:

Cat. No.: HY-174442
Target:  

PARP

Research Areas:  

Cancer

PARP1-IN-40 is a highly selectively and orally active PARP1 inhibitor (IC50: 0.19 nM for PARP1, 26 nM for PARP2). PARP1-IN-40 kills tumor cells by inhibiting PARP1, leading to accumulation of DNA damage. PARP1-IN-40 has high antitumor activity against BRCA mutant MDA-MB-436 cells. PARP1-IN-40 can be used in combination with chemotherapy for cancer-related research .
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