1 Result for "

PF-06658607

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PF-06658607" in MCE Product Catalog:

Cat. No.: HY-12679
CAS No.: 1621002-24-1
Target:  

Btk

Research Areas:  

Cancer

PF-06658607 is an alkynylated irreversible Brutons tyrosine kinase (BTK) inhibitor that covalently reacts with active site cysteines in the ATP-binding pocket. PF-06658607 can be used to detect "off "-targets for covalent kinase inhibitors in cancer cells. The alkyne moiety allows for azide-based detection probe via copper-catalyzed click chemistry .
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