1 Result for "

PI3Kα-IN-33

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PI3Kα-IN-33" in MCE Product Catalog:

Cat. No.: HY-183787
Target:  

PI3K Akt mTOR Apoptosis CDK

Research Areas:  

Cancer

PI3Kα-IN-33 is an orally active and selective PI3Kα inhibitor with an IC50 of 9.9 nM. PI3Kα-IN-33 blocks the PI3K/Akt/mTOR signaling pathway. PI3Kα-IN-33 induces apoptosis and triggers G2/M-phase arrest via Cyclin B1 and CDK1 downregulation. PI3Kα-IN-33 can be used for the research of colorectal cancer .
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