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PTH1 receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenylate Cyclase (1) Isotope-Labeled Compounds (1) PTHR (10) Thyroid Hormone Receptor (3)
By Research Areas:	Cancer (3) Endocrinology (3) Metabolic Disease (5) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P0059

Teriparatide 10+ Cited Publications Human parathyroid hormone-(1-34); hPTH (1-34)	PTHR Thyroid Hormone Receptor	Others Cancer
Teriparatide (Human parathyroid hormone-(1-34)) is a **PTH1 receptor** agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .

HY-P1852

TIP 39, Tuberoinfundibular Neuropeptide 1 Publications Verification	Adenylate Cyclase PTHR	Neurological Disease
TIP 39, Tuberoinfundibular Neuropeptide is an endogenous **PTH2 receptor agonist and antihypertensive agent. TIP 39, Tuberoinfundibular Neuropeptide selectively activates the PTH2 receptor with no activity on the PTH1 receptor**, stimulates cAMP production, activates adenylate cyclase, and elevates intracellular calcium levels via mobilization from intracellular stores. TIP 39, Tuberoinfundibular Neuropeptide is highly conserved in humans, mice, and rats. TIP 39, Tuberoinfundibular Neuropeptide is applicable to research related to nociception and inflammation-induced pain .

HY-P0059A

Teriparatide acetate hydrate Human parathyroid hormone-(1-34) acetate hydrate; hPTH (1-34) acetate hydrate	PTHR Thyroid Hormone Receptor	Others Cancer
Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) is a **PTH1 receptor** agonist. Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) can be used for osteoporosis research .

HY-176946

PTH1R agonist 4	PTHR	Metabolic Disease
PTH1R agonist 4 (Example 63) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC₅₀ value greater than 7. PTH1R agonist 4 can be used for the study of bone diseases, such as osteoporosis .

HY-113918

SW-106	PTHR	Metabolic Disease
SW-106 is a *parathyroid hormone receptor* 1 (PTHR1*) antagonist. SW106 antagonizes PTHR1-mediated cAMP signaling induced by the peptide analog, M-PTH (1-11), as well as by the native PTH (1-9) sequence, as tethered to the extracellular end of transmembrane domain (TMD) helix-1 of the receptor*. SW-106 can be used for the research of metabolic disease .

HY-176944

PTH1R agonist 2	PTHR	Metabolic Disease Endocrinology
PTH1R agonist 2 (example 3) is a parathyroid hormone 1 receptor (PTH1R) agonist. PTH1R agonist 2 can be used for research of hypoparathyroidism and osteoporosis .

HY-176945

PTH1R agonist 3	PTHR	Metabolic Disease
PTH1R agonist 3 (Example 47) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC₅₀ value of less than 6. PTH1R agonist 3 can be used for the study of bone diseases, such as osteoporosis .

HY-P0059S

Teriparatide-d10 Human parathyroid hormone-(1-34)-d₁₀; hPTH (1-34)-d₁₀	Isotope-Labeled Compounds PTHR Thyroid Hormone Receptor	Cancer
Teriparatide-d₁₀ (Human parathyroid hormone-(1-34)-d₁₀) is the deuterium labeled Teriparatide (HY-P0059). Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .

HY-176943

PTH1R agonist 1	PTHR	Metabolic Disease Endocrinology
PTH1R agonist 1 (Example 2) is a parathyroid hormone 1 receptor (PTH1R) agonist. PTH1R agonist 1 can be used for research of hypoparathyroidism and osteoporosis .

HY-179356

Octadecyl β-D-glucopyranosiduronic acid	PTHR	Endocrinology
Octadecyl β-D-glucopyranosiduronic acid (Compound 9) is a parathyroid hormone 1 receptor (PTH1R) activator, with a pEC₅₀ value > 9. Octadecyl β-D-glucopyranosiduronic acid can be used for research on hypoparathyroidism .

Cat. No.	Product Name	Target	Research Area

HY-P0059

Teriparatide 10+ Cited Publications Human parathyroid hormone-(1-34); hPTH (1-34)	PTHR Thyroid Hormone Receptor	Others Cancer
Teriparatide (Human parathyroid hormone-(1-34)) is a **PTH1 receptor** agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .

HY-P1852

TIP 39, Tuberoinfundibular Neuropeptide 1 Publications Verification	Adenylate Cyclase PTHR	Neurological Disease
TIP 39, Tuberoinfundibular Neuropeptide is an endogenous **PTH2 receptor agonist and antihypertensive agent. TIP 39, Tuberoinfundibular Neuropeptide selectively activates the PTH2 receptor with no activity on the PTH1 receptor**, stimulates cAMP production, activates adenylate cyclase, and elevates intracellular calcium levels via mobilization from intracellular stores. TIP 39, Tuberoinfundibular Neuropeptide is highly conserved in humans, mice, and rats. TIP 39, Tuberoinfundibular Neuropeptide is applicable to research related to nociception and inflammation-induced pain .

Species:	Human (1) Rat (1) Cynomolgus (1)
Tag:	His (3)
Source:	HEK293 (2) E. coli Cell-free (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71244

	PTH1R Protein, Human (HEK293, His) Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor; PTH1R	Human	HEK293
	PTH1R Protein, Human (HEK 293, His) is a recombinant PTH1R protein with a His-Flag. PTH1R plays an important role in skeletal development and homeostasis.

HY-P705968

	PTH1R Protein, Rat (HEK293, His) Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor (PTH/PTHr receptor); Parathyroid hormone 1 receptor (PTH1 receptor); PTH1r; PTHr, PTHr1	Rat	HEK293

HY-P705535

	PTH1R Protein, Cynomolgus (Cell-Free, His) Parathyroid hormone; parathyroid hormone-related peptide receptor; PTH; PTHrP type I receptor; Parathyroid hormone 1 receptor	Cynomolgus	E. coli Cell-free

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Cat. No.	Product Name	Chemical Structure

HY-P0059S

Teriparatide-d10
Teriparatide-d₁₀ (Human parathyroid hormone-(1-34)-d₁₀) is the deuterium labeled Teriparatide (HY-P0059). Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .

Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4)
Application:	IHC-P (2) ICC/IF (2) IP (2) WB (2) ELISA (2)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Monoclonal Antibody (1) Recombinant (2)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85340

	Parathyroid Hormone Receptor 1 Antibody (YA5032) PTH1R; PTHR; PTHR1; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor	WB, IP	Human
	Parathyroid Hormone Receptor 1 Antibody (YA5032) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Parathyroid Hormone Receptor 1.

HY-P81707

	Parathyroid Hormone Receptor 1 Antibody (YA1452) PTH1R; PTHR; PTHR1; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor	WB, IP	Human
	Parathyroid Hormone Receptor 1 Antibody (YA1452) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Parathyroid Hormone Receptor 1.

HY-P84478

	Parathyroid Hormone Receptor 1 Antibody (YA4175) PFE; PTHR; PTHR1; MGC138426; MGC138452; PTH1R	IHC-P, ICC/IF, ELISA	Human
	Parathyroid Hormone Receptor 1 Antibody (YA4175) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Parathyroid Hormone Receptor 1.

HY-P84478A

	Parathyroid Hormone Receptor 1 Antibody (YA4175)(PBS only) PFE; PTHR; PTHR1; MGC138426; MGC138452; PTH1R	IHC-P, ICC/IF, ELISA	Human
	Parathyroid Hormone Receptor 1 Antibody (YA4175) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Parathyroid Hormone Receptor 1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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