1 Result for "

Pan-Trk-IN-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Pan-Trk-IN-3" in MCE Product Catalog:

Cat. No.: HY-144069
CAS No.: 2763637-66-5
Target:  

Trk Receptor Apoptosis

Research Areas:  

Cancer

Pan-Trk-IN-3 (Compound 11g) is a potent inhibitor of pan-Trk and their drug-resistant mutants with IC50 values of 2, 3, 2, 21, 26, 5, 7 and 6 nM against TrkA, TrkB, TrkC, TrkA G595R, TrkA G667C, TrkA G667S, TrkA F589L and TrkC G623R, respectively. Pan-Trk-IN-3 displays excellent antitumor activity and induces apoptosis .
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