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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
Pregnenolone
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "Pregnenolone" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: 3β-Hydroxy-5-pregnen-20-one
7
7 Publications Verification
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate
Category:
7
7 Publications Verification
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium
Category:
6
Research Areas:
Pregnenolone 16α-carbonitrile is an orally active prototypical and effective rodent-PXR activator. Pregnenolone 16α-carbonitrile, a synthetic steroid, induces cytochrome P450 3A expression. Pregnenolone 16α-carbonitrile exhibits increased resistance to subsequent stressful insults .
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Category:
Human Gut Microbiota Metabolites Immune System Disorder Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Endocrinology Steroids
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Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer .
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MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents .
Research Areas:
Adenosine 3',5'-diphosphate disodium is an endogenous purine nucleotide. Adenosine 3',5'-diphosphate disodium acts as an inhibitor of bovine adrenal estrogen sulfotransferase (EST) with a Ki value of 7.0 μM. It also serves as an indispensable specific cofactor for the pregnenolone-binding protein (PBP) steroid-binding complex, with an EC50 value of 1.5 μM in guinea pigs .
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Pregnenolone acetate (compound #43), a nonmetabolized Pregnenolone (HY-B0151) analog, can promote neurite extension and induce a change in growth cone morphology in primary cultures of cerebellar granule neurons. Pregnenolone acetate, a neurosteroid, increases microtubule polymerization. Pregnenolone acetate has the potential for neurodevelopmental diseases research .
Cat. No.: HY-B0151S2
CAS No.: 61574-54-7
Synonyms: 3β-Hydroxy-5-pregnen-20-one-d4-1
Cat. No.: HY-110189S1
CAS No.: 1485492-21-4
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate-d4 sodium
Cat. No.: HY-113263R
CAS No.: 387-79-1
Synonyms: 17-OHP5 (Standard)
Research Areas:
17a-Hydroxypregnenolone (Standard) is the analytical standard of 17a-Hydroxypregnenolone. This product is intended for research and analytical applications. 17a-Hydroxypregnenolone is a metabolite of Pregnenolone (HY-B0151) and a precursor in the biosynthesis of Dehydroepiandrosterone (HY-14650). 17a-Hydroxypregnenolone is a substrate for the enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD) .
Synonyms: 17-OHP5-d3
Cat. No.: HY-B0151S
Synonyms: 3β-Hydroxy-5-pregnen-20-one-d4
Cat. No.: HY-B0151S1
CAS No.: 2483824-26-4
Synonyms: 3β-Hydroxy-5-pregnen-20-one-13C2,d2
Cat. No.: HY-W742214
Cat. No.: HY-110189R
CAS No.: 1852-38-6
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium (Standard)
Category:
Cat. No.: HY-110189S
CAS No.: 2483824-22-0
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium-13C2,d2
Cat. No.: HY-N13215
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Tongkat Ali Extract is the extract of Tongkat Ali, a testosterone modulator. Tongkat Ali Extract activates CYP17 enzyme to enhance conversion of pregnenolone and progesterone to dehydroepiandrosterone, androstenedione, and testosterone. Tongkat Ali Extract demonstrates antimalarial, antimicrobial, anticancer, and antidiabetic activity. Tongkat Ali Extract can be used for the research of diabetic and male infertility .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
