2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Cytochrome P450 Parasite Fungal
  4. Tongkat Ali Extract

Tongkat Ali Extract is the extract of Tongkat Ali, a testosterone modulator. Tongkat Ali Extract activates CYP17 enzyme to enhance conversion of pregnenolone and progesterone to dehydroepiandrosterone, androstenedione, and testosterone. Tongkat Ali Extract demonstrates antimalarial, antimicrobial, anticancer, and antidiabetic activity. Tongkat Ali Extract can be used for the research of diabetic and male infertility.

For research use only. We do not sell to patients.

Tongkat Ali Extract

Tongkat Ali Extract Chemical Structure

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Tongkat Ali Extract Related Antibodies

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A CYP3A4 CYP17A1

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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  • References

  • Customer Review

Description

Tongkat Ali Extract is the extract of Tongkat Ali, a testosterone modulator. Tongkat Ali Extract activates CYP17 enzyme to enhance conversion of pregnenolone and progesterone to dehydroepiandrosterone, androstenedione, and testosterone. Tongkat Ali Extract demonstrates antimalarial, antimicrobial, anticancer, and antidiabetic activity. Tongkat Ali Extract can be used for the research of diabetic and male infertility[1][2][3][4].

IC50 & Target[1]

CYP17

 

In Vitro

Tongkat Ali Extract (24 h) exhibits antibacterial activity against Bacillus cereus, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Salmonella typhi[5].
Tongkat Ali Extract (48 h) shows positive antifungal activity against C. albicans and A. fumigatus[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tongkat Ali Extract Related Antibodies
In Vivo

Tongkat Ali Extract (200-800 mg/kg; p.o.; daily; 14 days) significantly improves multiple male reproductive parameters in rats, while showing no detrimental effects on reproductive organ weights[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats (adult male, 300-350 g)[4]
Dosage: 200; 800 mg/kg
Administration: p.o.; daily; 14 days
Result: Decreased body weight by 5.7% at 800 mg/kg.
Decreased omentum fat mass by 31.9% at 800 mg/kg.
Increased serum testosterone concentration by 30.2% at 800 mg/kg.
Increased sperm concentration by 54.9% at 800 mg/kg.
Increased sperm vitality by 21.9% at 800 mg/kg.
Increased total sperm motility by 3.5% at 800 mg/kg.
Increased progressive sperm motility by 8.3% at 800 mg/kg.
Increased sperm velocity average path (VAP) by 11.2% at 800 mg/kg.
Increased sperm velocity curve line (VCL) by 10.6% at 800 mg/kg.
Increased sperm velocity straight line (VSL) by 13.2% at 800 mg/kg.
Increased sperm with intact mitochondrial membrane potential by 25.1% at 800 mg/kg.
Decreased body weight significantly at 200 mg/kg.
Decreased omentum fat mass at 200 mg/kg.
Increased sperm concentration, vitality, total motility, progressive motility, VAP, VCL, and VSL significantly at 200 mg/kg.
Showed no significant changes in testes, epididymides, prostate, or gastrocnemius muscle weights at either dose.
Detected no effect on acrosome reaction status at either dose.
Appearance

Solid

Color

Yellow to brown

SMILES

[Tongkat Ali Extract]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

RT, sealed storage, away from moisture and light

In solvent -80°C 1 year
-20°C 6 months
Purity & Documentation
References
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Tongkat Ali Extract Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tongkat Ali ExtractBacterialCytochrome P450ParasiteFungalCYPsprogesteronedehydroepiandrosteronesex hormone-binding globulinlate-onset hypogonadismmale infertilitypregnenolonetestosteroneSprague-Dawley ratsandrostenedioneCYP17 enzymeInhibitorinhibitorinhibit

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