105078-92-0
Chemical Structure
17a-Hydroxypregnenolone-d3
Synonym(s): 17-OHP5-d3
- CAS No.: 105078-92-0
- Formula:C21H29D3O3
- Molecular Weight:335.50
IUPAC Name: 1-((3S,8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one-2,2,2-d3
InChIKey: JERGUCIJOXJXHF-DBAXYKBZSA-N
SMILES: C[C@@]12[C@](CC[C@]2(O)C(C([2H])([2H])[2H])=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
Biological Activity: 17a-Hydroxypregnenolone-d3 (17-OHP5-d3) is the deuterium labeled 17a-Hydroxypregnenolone (HY-113263). 17a-Hydroxypregnenolone is a metabolite of Pregnenolone (HY-B0151) and a precursor in the biosynthesis of Dehydroepiandrosterone (HY-14650). 17a-Hydroxypregnenolone is a substrate for the enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD)[1][2].
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17a-Hydroxypregnenolone-d3 | 96.27% | 17a-Hydroxypregnenolone-d3 (17-OHP5-d3) is the deuterium labeled 17a-Hydroxypregnenolone (HY-113263). 17a-Hydroxypregnenolone is a metabolite of Pregnenolone (HY-B0151) and a precursor in the biosynthesis of Dehydroepiandrosterone (HY-14650). 17a-Hydroxypregnenolone is a substrate for the enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD). | ||||||||||||||||||||
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17a-Hydroxypregnenolone (Standard) | 99.29% | 17a-Hydroxypregnenolone (Standard) is the analytical standard of 17a-Hydroxypregnenolone. This product is intended for research and analytical applications. 17a-Hydroxypregnenolone is a metabolite of Pregnenolone (HY-B0151) and a precursor in the biosynthesis of Dehydroepiandrosterone (HY-14650). 17a-Hydroxypregnenolone is a substrate for the enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD). | ||||||||||||||||||||
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17α-Hydroxypregnenolone-13C2,d2 | 17α-Hydroxypregnenolone-13C2,d2 is the deuterium and 13C labeled 17α-Hydroxypregnenolone. 17a-Hydroxypregnenolone is a metabolite of Pregnenolone (HY-B0151) and a precursor in the biosynthesis of Dehydroepiandrosterone (HY-14650). 17a-Hydroxypregnenolone is a substrate for the enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD). | |||||||||||||||||||||
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17a-Hydroxypregnenolone | 99.61% | 17a-Hydroxypregnenolone (17-OHP5) is a metabolite of Pregnenolone (HY-B0151) and a precursor in the biosynthesis of Dehydroepiandrosterone (HY-14650). 17a-Hydroxypregnenolone is a substrate for the enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD). | ||||||||||||||||||||
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- [1]. Petrunak EM, et al. Structures of human steroidogenic cytochrome P450 17A1 with substrates. J Biol Chem. 2014 Nov 21;289(47):32952-64. [Content Brief]
- [2]. Fiet J, et al. Plasma 17-OH pregnenolone: comparison of a time-resolved fluoroimmunoassay using a new tracer 17-OH pregnenolone-3-oxyacetyl-biotine with a radioimmunoassay using 125I 17-OH pregnenolone-3-hemisuccinate-histamine. Steroids. 2001 Feb;66(2):81-6. [Content Brief]
