17α-Hydroxypregnenolone-13C2,d2
17α-Hydroxypregnenolone-13C2,d2 is the deuterium and 13C labeled 17α-Hydroxypregnenolone. 17a-Hydroxypregnenolone is a metabolite of Pregnenolone (HY-B0151) and a precursor in the biosynthesis of Dehydroepiandrosterone (HY-14650). 17a-Hydroxypregnenolone is a substrate for the enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD).
For research use only. We do not sell to patients.
- CAS No.: 2483824-29-7
- Formula: C1913C2H30D2O3
- Molecular Weight:336.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2483824-29-7
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Unlabeled Cas 387-79-1
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Molecular Weight 336.47
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Formula C1913C2H30D2O3
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SMILES
C[C@@]12[C@](CC([2H])([2H])[C@]2(O)[13C]([13CH3])=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
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Synonyms
17-OHP5-13C2,d2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Petrunak EM, et al. Structures of human steroidogenic cytochrome P450 17A1 with substrates. J Biol Chem. 2014 Nov 21;289(47):32952-64. [Content Brief]
[2]. Fiet J, et al. Plasma 17-OH pregnenolone: comparison of a time-resolved fluoroimmunoassay using a new tracer 17-OH pregnenolone-3-oxyacetyl-biotine with a radioimmunoassay using 125I 17-OH pregnenolone-3-hemisuccinate-histamine. Steroids. 2001 Feb;66(2):81-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
17α-Hydroxypregnenolone-13C2,d2 Related Classifications
HY-113263S1 Related Classifications
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