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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Pyruvate kinase liver
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Pyruvate kinase liver" in MCE Product Catalog:
Cat. No.: HY-112253
CAS No.: 15978-08-2
Target:
Cat. No.: HY-161337
CAS No.: 3078059-66-9
Target:
Research Areas:
PKL-IN-1 is a potent inhibitor of pyruvate kinase (PKL) with an IC50 of 0.07 μM. PKL-IN-1 can be used in the study of non-alcoholic fatty liver disease .
Cat. No.: HY-165154
CAS No.: 35663-85-5
Synonyms: Desdanine; Pyracrimycin A
Category:
Cat. No.: HY-168337
CAS No.: 3052985-32-4
Target:
SET-171 is a JNK (c-Jun N-terminal kinase) inhibitor that exhibits significant anticancer activity and lipid metabolism regulation by inhibiting liver pyruvate kinase (PKL) expression. In anticancer studies, SET-171 shows IC50 values of 8.82 μM and 2.97 μM against HepG2 and Huh7 cell lines, respectively, indicating high cytotoxicity. Additionally, in non-alcoholic fatty liver disease (NAFLD)-related studies, SET-171 significantly reduces triacylglycerol (TAG) levels and inhibits the expression of steatosis-related proteins. SET-171 holds promise for research on hepatocellular carcinoma (HCC) and NAFLD .
Cat. No.: HY-P71210
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PKLR; Pyruvate kinase, liver And Blood Cell; Pyruvate kinase L/R; Pyruvate kinase Isozymes R/L; Pyruvate kinase, liver And RBC; Pyruvate kinase Isozyme R/L; Red Cell/liver Pyruvate kinase; Pyruvate kinase Isoform 1; R-Type/L-Type Pyruvate kinase; Pyruvate
Species:
Human
Source:
HEK293
Cat. No.: HY-P700578
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PKLR; Pyruvate kinase, liver And Blood Cell; Pyruvate kinase L/R; Pyruvate kinase Isozymes R/L; Pyruvate kinase, liver And RBC; Pyruvate kinase Isozyme R/L; Red Cell/liver Pyruvate kinase; Pyruvate kinase Isoform 1; R-Type/L-Type Pyruvate kinase; Pyruvate
Species:
Rat
Source:
P. pastoris
Cat. No.: HY-P83644
Synonyms: PKM2 (Phospho Tyr105); PKM2 (Phospho Y105); PK 1; PK 2; PK 3; PK Muscle type; PK1; PK2; Pk3; PKL; PKLR; PKM 2; PKM; PYKM; Pyruvate kinase 1; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozyme R/L; Pyruvate kinase isozymes M1/M2; Pyruvate kinase liver and blood cell; Pyruvate kinase liver and RBC; Pyruvate kinase liver and RBC type; Pyruvate kinase M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; Pyruvate kinase type L; R type/L type Pyruvate kinase; Red cell/liver Pyruvate kinase; RPK; TCB; THBP 1; THBP1; Thyroid hormone binding protein cytosolic; CTHBP; Cytosolic thyroid hormone binding protein; MGC3932; OIP 3; Oip3; Tumor M2-PK; p58; OIP-3.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
