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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
R-L3 (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "R-L3 (Standard)" in MCE Product Catalog:
Cat. No.: HY-108591R
CAS No.: 103342-82-1
Synonyms: R-L3 (Standard)
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L-364,373 (Standard) is the analytical standard of L-364,373 (HY-108591). This product is intended for research and analytical applications. L-364,373 (R-L3) is a voltage-gated Kv7.1 (KCNQ1)/mink channels activator. L-364,373 activates Iks (slow delayed rectifier potassium current) and shortens action potential duration in guinea pig cardiac myocytes, and suppresses early afterdepolarizations in rabbit ventricular myocytes .
Cat. No.: HY-13326R
CAS No.: 1097917-15-1
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ASP3026 (Standard) is the analytical standard of ASP3026. This product is intended for research and analytical applications. ASP3026 is a selective and orally active inhibitor of anaplastic lymphoma kinase (ALK). ASP3026 is a selective and oral active anaplastic lymphoma kinase (ALK) inhibitor with a IC50 value of 3.5 nM. ASP3026 can inhibit the phosphorylation of IGF-1R, STAT3, AKT and JNK proteins, and induce the cleavage of caspase 3 and PARP. It also inhibited ROS and ACK. ASP3026 can be used in anti-tumor research .
Cat. No.: HY-45119R
CAS No.: 1215192-62-3
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(3aR,4R,5R,6aS)-2-Oxo-4-((R,E)-3-oxo-4-(m-tolyl)pent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate (Standard) is the analytical standard of (3aR,4R,5R,6aS)-2-Oxo-4-((R,E)-3-oxo-4-(m-tolyl)pent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate. This product is intended for research and analytical applications.
Cat. No.: HY-77964R
CAS No.: 220352-36-3
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(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid (Standard) is the analytical standard of (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid. This product is intended for research and analytical applications.
Cat. No.: HY-Z4409R
CAS No.: 1151240-91-3
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(R)-Ethyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate (Sitagliptin Impuruity) (Standard) is the analytical standard of (R)-Ethyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate (Sitagliptin Impuruity). This product is intended for research and analytical applications.
Cat. No.: HY-W714686R
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(R)-4-(3-(Methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol (Standard) is the analytical standard of (R)-4-(3-(Methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol. This product is intended for research and analytical applications.
Cat. No.: HY-100218CR
CAS No.: 1219810-15-7
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(1R,3R)-RSL3 (Standard) is the analytical standard of (1R,3R)-RSL3 (HY-100218C). This product is intended for research and analytical applications. (1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells .
Cat. No.: HY-128720R
CAS No.: 759-65-9
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Cat. No.: HY-78628R
CAS No.: 1206524-79-9
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1-(tert-Butyl) 2-methyl (2S,4R)-4-((3-chloro-7-methoxyquinoxalin-2-yl)oxy)pyrrolidine-1,2-dicarboxylate (Standard) is the analytical standard of 1-(tert-Butyl) 2-methyl (2S,4R)-4-((3-chloro-7-methoxyquinoxalin-2-yl)oxy)pyrrolidine-1,2-dicarboxylate. This product is intended for research and analytical applications.
Cat. No.: HY-103558R
CAS No.: 191471-52-0
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LY379268 (Standard) is the analytical standard of LY379268 (HY-103558). This product is intended for research and analytical applications. LY379268 is a potent, selective and brain-penetrant mGlu2/3R agonist with EC50 values of 2.69 nM (mGlu2) and 4.48 nM (mGlu3). LY379268 has no activity on human mGlu 1a, 4a, 5a or 7a receptors. LY379268 has antioxidant and neuroprotective effects .
Cat. No.: HY-I1122R
CAS No.: 2452300-89-7
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(2S,3R,4R,5S,6R)-2-(3-(4-Ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (Standard) is the analytical standard of (2S,3R,4R,5S,6R)-2-(3-(4-Ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (HY-I1122). This product is intended for research and analytical applications.
Cat. No.: HY-100218AR
CAS No.: 1219810-16-8
Synonyms: (1S,3R)-RSL3 (Standard)
Research Areas:
RSL3 (Standard) is the analytical standard of RSL3 (HY-100218A). This product is intended for research and analytical applications. RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells .
Cat. No.: HY-103130R
CAS No.: 1171123-46-8
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EMD386088 (Standard) is the analytical standard of EMD386088 (HY-103130). This product is intended for research and analytical applications. EMD386088 is a potent and selective 5-HT6 receptor (5-HT6R) agonist with an EC50 of 1.0 nM. EMD-386088 is inactive against other HT receptors except 5-HT3R (IC50 of 34 nM). EMD386088 regulates the activity of ERK1/2. EMD386088 has the potential for the research of alzheimer's disease (AD) and schizophrenia .
Cat. No.: HY-10624R
CAS No.: 312637-48-2
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THIQ (Standard) is the analytical standard of THIQ (HY-10624). This product is intended for research and analytical applications. THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2 nM, EC50=2.1 nM) and rMC4R (IC50=0.6 nM, EC50=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
