103342-82-1
103342-82-1
Chemical Structure
L-364,373
Synonym(s): R-L3
- CAS No.: 103342-82-1
- Formula:C25H20FN3O
- Molecular Weight:397.44
IUPAC Name: (R)-3-((1H-indol-3-yl)methyl)-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
InChIKey: CGBANSGENFERAT-JOCHJYFZSA-N
SMILES: O=C1N(C)C2=CC=CC=C2C(C3=CC=CC=C3F)=N[C@@H]1CC4=CNC5=C4C=CC=C5
Biological Activity: L-364,373 (R-L3) is a voltage-gated Kv7.1 (KCNQ1)/mink channels activator. L-364,373 activates Iks (slow delayed rectifier potassium current) and shortens action potential duration in guinea pig cardiac myocytes, and suppresses early afterdepolarizations in rabbit ventricular myocytes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-364,373 | 99.65% | L-364,373 (R-L3) is a voltage-gated Kv7.1 (KCNQ1)/mink channels activator. L-364,373 activates Iks (slow delayed rectifier potassium current) and shortens action potential duration in guinea pig cardiac myocytes, and suppresses early afterdepolarizations in rabbit ventricular myocytes. | ||||||||||||||||||||
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L-364,373 (Standard) | ≥98% | L-364,373 (Standard) is the analytical standard of L-364,373 (HY-108591). This product is intended for research and analytical applications. L-364,373 (R-L3) is a voltage-gated Kv7.1 (KCNQ1)/mink channels activator. L-364,373 activates Iks (slow delayed rectifier potassium current) and shortens action potential duration in guinea pig cardiac myocytes, and suppresses early afterdepolarizations in rabbit ventricular myocytes. | ||||||||||||||||||||
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