1 Result for "

R428 (GMP)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "R428 (GMP)" in MCE Product Catalog:

Cat. No.: HY-15150G
CAS No.: 1037624-75-1
Synonyms: R428 (GMP); BGB324 (GMP)
Bemcentinib (R428) GMP is Bemcentinib (HY-15150) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy.Bemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer .
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