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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
RA-2
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "RA-2" in MCE Product Catalog:
Cat. No.: HY-118689
CAS No.: 1867107-62-7
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
RA-2 is a negative-gating modulator of KCa2/3 channels with an IC50 of 17 nM. RA-2 inhibits bradykinin-induced endothelium-derived hyperpolarization (EDH)-type relaxation in U46619-precontracted rings. RA-2 can help to define the physiologic and pathomechanistic roles of KCa2/3 in the vasculature, central nervous system, and during inflammation .
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2 Cited Publications
Cat. No.: HY-P1848
CAS No.: 395069-86-0
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Cat. No.: HY-P11287A
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A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively .
Cat. No.: HY-P10292
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MRS1334 is a potent and selective human adenosine A3 receptor antagonist with Kis of 2.69 nM, >100 nM, >100 nM for hA3, rA1, rA2A, respectively. MRS1334 blocks the protective effect of Cl-IB-MECA leading to significant bradycardia and elevated ST segment [2]. MRS1334 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-P990086
CAS No.: 2733581-99-0
Synonyms: RG-6292; RO-7296682
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Cat. No.: HY-N4260
CAS No.: 83459-42-1
Category:
Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae
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Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine . Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA) .
Cat. No.: HY-P11287
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Cat. No.: HY-103177
CAS No.: 591771-91-4
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PSB-10 hydrochloride is a potent and selective antagonist of human adenosine A3 receptor (A3AR), with a Ki of 0.44 nM. PSB-10 hydrochloride shows more than 800-fold selectivity for hA3 over rA1, rA2A, hA1, hA2A and hA2B receptors (Ki=805, 6040, 1700, 2700, 30000 nM, respectively). PSB-10 hydrochloride produces thermal hyperalgesia in mice [2].
Cat. No.: HY-174618
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Human IL22RA2 mRNA encodes the human interleukin 22 receptor subunit alpha 2 (IL22RA2) protein, a member of the class II cytokine receptor family. IL22RA2 may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon.
Cat. No.: HY-174637
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Human IL13RA2 mRNA encodes the human interleukin 13 receptor subunit alpha 2 (IL13RA2) protein, a subuint of the interleukin 13 receptor complex. IL13RA2 binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.
Cat. No.: HY-RS06689
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IL13RA2 Human Pre-designed siRNA Set A contains three designed siRNAs for IL13RA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06738
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IL22RA2 Human Pre-designed siRNA Set A contains three designed siRNAs for IL22RA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18438
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Il13ra2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il13ra2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24920
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Il13ra2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il13ra2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-167905
CAS No.: 867054-13-5
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ATL444 is a adenosine receptor antagonist, with Ki values of 7.0, 2.5, 61.8, >1000 nM for rA1AR, rA2AAR, rA2BAR, rA3AR, respectively .
Cat. No.: HY-107495R
CAS No.: 5452-87-9
Synonyms: NSC19005 (Standard)
Research Areas:
Betahistine EP Impurity C (Standard) is the analytical standard of Betahistine EP Impurity C. This product is intended for research and analytical applications. Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine . Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
