1 Result for "

S1PR1/S1PR5 agonist-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "S1PR1/S1PR5 agonist-1" in MCE Product Catalog:

Cat. No.: HY-181875
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

S1PR1/S1PR5 agonist-1 (Compound 19) is an orally active S1PR1 and S1PR5 agonist with EC50 values of 40.0 and 22.9 nM, respectively. S1PR1/S1PR5 agonist-1 binds to key residues of S1PR1 to mediate agonistic activity. S1PR1/S1PR5 agonist-1 alleviates colitis pathological changes in DSS-induced mouse models and exerts minimal effects on mouse heart rate. S1PR1/S1PR5 agonist-1 can be used for the research of inflammatory bowel disease .
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