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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
SA-1
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "SA-1" in MCE Product Catalog:
10
10 Publications Verification
Target:
Domaines de recherche:
ML-SA1, as a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral [1].
4
4 Cited Publications
Target:
Domaines de recherche:
ML-SA5 is a potent TRPML1 cation channel agonist that activates the entire endosomal TRPML1 (ML1) current in DMD myocytes with an EC50 of 285 nM and is more potent than ML-SA1. ML-SA5 has anticancer activity and can inhibit tumour growth [1].
3
3 Cited Publications
Target:
Domaines de recherche:
GNE-1858 is a potent and ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor, with IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA, respectively [1].
Cat. No.: HY-NP163D
Synonyms: WGA-AF594
Cat. No.: HY-P5261
CAS No.: 2673230-58-3
Synonyms: KP1
Target:
Domaines de recherche:
Cat. No.: HY-NP163E
Synonyms: WGA-AF647
Cat. No.: HY-NP163
Synonyms: WGA-AF350
Cat. No.: HY-NP163I
Synonyms: WGA-AF 680
Cat. No.: HY-NP163J
Synonyms: WGA-AF 405
Cat. No.: HY-128024
CAS No.: 956189-91-6
Target:
Domaines de recherche:
VHR-IN-1 (Compound SA1) is a potent and selective VHR phosphatase inhibitor with an IC50 of 18 nM. VHR-IN-1 can inhibit the proliferation of cervix cancer cells and has anti-tumor activity [1].
Cat. No.: HY-108462R
CAS No.: 332382-54-4
Domaines de recherche:
ML-SA1 (Standard) is the analytical standard of ML-SA1 (HY-108462). This product is intended for research and analytical applications. ML-SA1, as a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral [1].
Cat. No.: HY-RS13866
Target:
Domaines de recherche:
STAG1 Human Pre-designed siRNA Set A contains three designed siRNAs for STAG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-NP163H
Synonyms: WGA-AF750
Cat. No.: HY-101266A
CAS No.: 1398569-75-9
Synonyms: DS-3032 tosylate
Milademetan tosylate is the tosylate salt form of Milademetan (HY-101266). Milademetan tosylate is an orally active inhibitor for MDM2. Milademetan tosylate arrests the cell cycle at G1 pahse, induces the apoptosis Milademetan tosylate restores the p53 activity by targeting the p53-MDM2 interaction, and exhibits anticancer activity against Merkel cell carcinoma (MCC) [1].
Cat. No.: HY-154869
CAS No.: 2924403-17-6
Target:
Domaines de recherche:
PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-34 inhibits tumor growth by activating the immune microenvironment [1].
Cat. No.: HY-RS21770
Target:
Domaines de recherche:
Stag1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Stag1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-NP163B
Synonyms: WGA-AF532
Cat. No.: HY-NP163K
Synonyms: WGA-AF 430
Cat. No.: HY-P704053
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Major outer membrane porin, serovar A; MOMP; ompA; omp1A; SA1/OT / Serovar A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
