2418670-70-7
2418670-70-7
Chemical Structure
ML-SA5
- CAS. Nr.: 2418670-70-7
- Formula:C19H24ClN3O4S2
- Molecular Weight:457.99
IUPAC Name: N1-(3-chloro-2-(piperidin-1-yl)phenyl)-N4,N4-dimethylbenzene-1,4-disulfonamide
InChIKey: YPPWKTIVYUTTEH-UHFFFAOYSA-N
SMILES: O=S(NC1=C(N2CCCCC2)C(Cl)=CC=C1)(C3=CC=C(S(=O)(N(C)C)=O)C=C3)=O
Biological Activity:
ML-SA5 is a potent TRPML1 cation channel agonist that activates the entire endosomal TRPML1 (ML1) current in DMD myocytes with an EC50 of 285 nM and is more potent than ML-SA1. ML-SA5 has anticancer activity and can inhibit tumour growth[1].
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ML-SA5 | 99.69% | ML-SA5 is a potent TRPML1 cation channel agonist that activates the entire endosomal TRPML1 (ML1) current in DMD myocytes with an EC50 of 285 nM and is more potent than ML-SA1. ML-SA5 has anticancer activity and can inhibit tumour growth. |
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References
Keywords
