PD-1/PD-L1-IN-34
PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-34 inhibits tumor growth by activating the immune microenvironment.
For research use only. We do not sell to patients.
- CAS No.: 2924403-17-6
- Formula: C35H33ClN2O3
- Molecular Weight:565.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2924403-17-6
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Molecular Weight 565.10
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Formula C35H33ClN2O3
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SMILES
CC1=C([C@@H]2[C@@H](C3=CC(OCC4=CC=CC(C#N)=C4)=C(C=C3Cl)CNC(C)(C(O)=O)C)C2)C=CC=C1C5=CC=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)