2924403-17-6
2924403-17-6
Chemical Structure
PD-1/PD-L1-IN-34
- CAS No.: 2924403-17-6
- Formula:C35H33ClN2O3
- Molecular Weight:565.10
InChIKey: ZFEYTBYBRIZPJN-IHLOFXLRSA-N
SMILES: CC1=C([C@@H]2[C@@H](C3=CC(OCC4=CC=CC(C#N)=C4)=C(C=C3Cl)CNC(C)(C(O)=O)C)C2)C=CC=C1C5=CC=CC=C5
Biological Activity: PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-34 inhibits tumor growth by activating the immune microenvironment[1].
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PD-1/PD-L1-IN-34 | PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-34 inhibits tumor growth by activating the immune microenvironment. | |||||||||||||||||||||
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References
Keywords
