1 Result for "

SDUY 127

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SDUY 127" in MCE Product Catalog:

Cat. No.: HY-183936
Target:  

SHP2 p38 MAPK ERK

Research Areas:  

Cancer

SDUY127 is a bivalent SHP2 inhibitor with an IC50 value of 16 nM. SDUY127 binds simultaneously to the tunnel allosteric site and latch allosteric site of SHP2 at a 1:1 stoichiometric ratio, stabilizes the protein in an inactive conformation, and induces sustained inhibition of the MAPK signaling pathway. SDUY127 can be used in research related to leukemia and hepatocellular carcinoma .
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