1 Result for "

SDUY104

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SDUY104" in MCE Product Catalog:

Cat. No.: HY-184412
Target:  

SHP2 Apoptosis p38 MAPK

Research Areas:  

Cancer

SDUY104 is an orally active amide-based allosteric inhibitor of SHP2 with an IC50 of 140 nM. SDUY104 impairs KRAS-driven pancreatic cancer cell proliferation via cell-cycle arrest and apoptosis. SDUY104 suppresses MAPK signaling and triggers compensatory PI3K-AKT activation. SDUY104 can be used for KRAS-mutant pancreatic cancer research .
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