1 Result for "

SKI-V

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SKI-V" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-12895
CAS No.: 24418-86-8
Purity:  98.95%
Target:  

SphK PI3K Apoptosis

Research Areas:  

Cancer

SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity .
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