1 Result for "

SKVLB1 cells

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "SKVLB1 cells" in MCE Product Catalog:

Cat. No.: HY-182633
CAS No.: 159542-04-8
Target:  

P-glycoprotein

Research Areas:  

Cancer

Hapalosin is a multidrug resistance reversal agent and chemosensitizer with mild cytotoxicity against cancer cells. Hapalosin inhibits the ATP-dependent drug efflux pump function of P-glycoprotein and antagonizes multidrug resistance-associated proteins. Hapalosin reverses multidrug resistance mediated by P-glycoprotein and multidrug resistance-associated proteins, increases the intracellular accumulation of drugs transported by P-glycoprotein, and enhances the cytotoxicity of these drugs against cancer cells overexpressing P-glycoprotein. Hapalosin can be used in the research of multidrug-resistant cancers .
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