1 Result for "

SMARCA2BD

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SMARCA2BD" in MCE Product Catalog:

Cat. No.: HY-161882
CAS No.: 2669027-50-1
Target:  

PROTACs SWI/SNF Complex

Domaines de recherche:  

Cancer

PROTAC SMARCA2 degrader-8 is a SMARCA2 PROTAC degrader with a DC50 of 28 nM in A375 cells. PROTAC SMARCA2 degrader-8 forms a crystallizable ternary complex with the SMARCA4 bromodomain and VBC, promoting the ubiquitination and proteasomal degradation of SMARCA2. PROTAC SMARCA2 degrader-8 can be used in melanoma research .
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