47 Results for "

SNAP-tagged

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "SNAP-tagged" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-131015
CAS No.: 2080306-25-6
Purity:  99.28%
Research Areas:  

Others

HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling .
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Cat. No.: HY-W017776
CAS No.: 674799-96-3
Synonyms: SNAP-NH2
BG-NH2 is a pharmaceutical intermediate. BG-NH2 is suitable for synthesizing fluorescent SNAP tag substrates to label RNA .
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Cat. No.: HY-151645
CAS No.: 1104822-07-2
Purity:  99.32%
Target:  

ADC Linkers

Research Areas:  

Others

Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .
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Cat. No.: HY-131028
Purity:  ≥95.0%
Synonyms: JF646 TFA
Janelia Fluor 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute (Ex/Em = 646/664 nm).
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Cat. No.: HY-151646
Purity:  99.59%
Synonyms: Alkyne-PEG5-BG
Target:  

ADC Linkers

Research Areas:  

Others

Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-136936
CAS No.: 2068027-79-0
Purity:  98.27%
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .
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Cat. No.: HY-130736
CAS No.: 1811539-32-8
Synonyms: JF549, SE; JF549, NHS
Janelia Fluor? 549, SE (JF549, SE) is a cell-permeable fluorescent dye with an NHS ester (succinimidyl ester (SE)) reactive group. NHS esters react with primary amines and are commonly used to conjugate dyes to proteins, antibodies, amine-modified oligonucleotides, and other molecules. Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor? 549, SE also acts as a ligand for self-labeling tags such as HaloTag and SNAP-tag, and can be used in live-cell imaging studies (Ex/Em = 549 nm/571 nm) .
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Cat. No.: HY-139162
CAS No.: 1151762-33-2
Purity:  99.47%
Research Areas:  

Others

BGN3 is a good substrate for the SNAP-tag ? and H 5 enzymes. The activities of SNAP-tag ? and H 5 enzymes on BGN3 are reasonable (IC50= 15.6 and 23.5 μM, respectively) . BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-148958
CAS No.: 471918-16-8
SNAP-Biotin is a biotin-labeled SNAP tag probe. SNAP-Biotin can be used for protein biotinylation .
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Cat. No.: HY-139163
CAS No.: 2996069-91-9
Purity:  98.16%
Research Areas:  

Others

BGSN3 is a good substrate for the SNAP-tag ? and H 5 enzymes. The activities of SNAP-tag ? and H 5 enzymes on BGSN3 are reasonable (IC50=17.8 and 10 μM, respectively) . BGSN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-D2965
CAS No.: 1219603-04-9
Synonyms: SPG1
SNAP-Peroxy-Green-1 (SPG1) a SNAP tag fluorescent probe. SNAP-Peroxy-Green-1 can be used for detecting H2O2 in the extracellular space or on the surface of the cell membrane .
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Cat. No.: HY-175417
Target:  

PROTACs

Research Areas:  

Cancer

VHL-SNAP2-5C is a SNAP-fusion protein PROTAC degrader basing on a self-labeling protein SNAP tag. VHL-SNAP2-5C by endogenous tagging enables the visualization and the selective depletion of a SNAP-fusion protein, such as CLCa andEGFP .
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Cat. No.: HY-136937
CAS No.: 2067339-51-7
PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-D2933
SNAP-505 is a green fluorescent O6 benzylguanine derivative. SNAP-505 labels SNAP-tagged proteins covalently. SNAP-505 can be used to label cells (green) .
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Cat. No.: HY-146272
CAS No.: 2648650-50-2
Target:  

Vasopressin Receptor

Research Areas:  

Endocrinology

Vasopressin V2 receptor antagonist 1 is a vasopressin V2 receptor (V2R) antagonist with a Ki value of 3.8 nM. Vasopressin V2 receptor antagonist 1 inhibits renal cyst formation in embryonic renal cyst models and mouse models. Vasopressin V2 receptor antagonist 1 can be used in research related to autosomal dominant polycystic kidney disease .
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Cat. No.: HY-D2949
CAS No.: 2836233-28-2
SNAP-549 is a DY-549P1-labeled SNAP tag fluorescent probe, specifically designed for single-molecule imaging and dynamic tracking of proteins in living cells. SNAP-549 only labels SNAP-tag fusion proteins, with low background signals and forming irreversible connections, making it suitable for long-term observation .
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Cat. No.: HY-D2944
CAS No.: 1627942-39-5
SNAP-649 is a DY-649P1-labeled SNAP tag fluorescent probe.
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Cat. No.: HY-D2926
Synonyms: BG-Tz; SNAP-Tetrazine
BG-Tetrazine (BG-Tz; SNAP-Tetrazine) is a SNAP tag substrate that contains a methyl tetrazine group. BG-Tetrazine can specifically covalently label the target protein of the intracellular SNAP-tag fusion. The tetrazine group it carries can rapidly and efficiently undergo a bioorthogonal reaction with functional groups such as trans cyclooctene (TCO), thereby enabling multiple labeling, functionalization or enrichment of proteins. BG-Tetrazine can be applied in click chemistry .
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Cat. No.: HY-D2931
CAS No.: 1154528-97-8
SNAP-FAM is a FAM-labeled SNAP tag fluorescent probe, specifically designed for live-cell protein labeling and real-time imaging applications .
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Cat. No.: HY-D2929
CAS No.: 2461569-42-4
Synonyms: SNAP-JF585
BG-JF585 is Benzylguanine-conjugated JF585 (HY-131025). Benzylguanine is the substrate for SNAP tags. JF585 is a fluorophore (λabs: 593 nm; λem: 611 nm).
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