1 Result for "

SNORD116

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "SNORD116" in MCE Product Catalog:

製品番号: HY-161759
CAS 番号: 3107476-89-8
研究分野:  

Endocrinology Cancer

MS152 is an orally active, blood-brain barrier penetrant inhibitor of EHMT2/G9a and EHMT1/GLP, with IC50s of 76 nM and 126 nM, repsectively. MS152 reduces H3K9me2 levels and reactivates maternally silenced Prader-Willi syndrome (PWS) genes. MS152 significantly improves perinatal lethality and growth retardation in mouse models, and is applicable to research related to Prader-Willi syndrome .
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