3107476-89-8

MS152 Chemical Structure
3107476-89-8

Chemical Structure

MS152

  • CAS No.: 3107476-89-8
  • Formula:C22H31N3O3
  • Molecular Weight:385.50

InChIKey: SNDNHGBMPQNJKI-UHFFFAOYSA-N

SMILES: COC1=CC2=C(C=C1OCCCN3CCCC3)N=C(N)C=C2C4CCOCC4

Biological Activity: MS152 is an orally active, blood-brain barrier penetrant inhibitor of EHMT2/G9a and EHMT1/GLP, with IC50s of 76 nM and 126 nM, repsectively. MS152 reduces H3K9me2 levels and reactivates maternally silenced Prader-Willi syndrome (PWS) genes. MS152 significantly improves perinatal lethality and growth retardation in mouse models, and is applicable to research related to Prader-Willi syndrome[1].

Cat. No. Product Name Purity Description Pricing
HY-161759 		MS152 99.36% MS152 is an orally active, blood-brain barrier penetrant inhibitor of EHMT2/G9a and EHMT1/GLP, with IC50s of 76 nM and 126 nM, repsectively. MS152 reduces H3K9me2 levels and reactivates maternally silenced Prader-Willi syndrome (PWS) genes. MS152 significantly improves perinatal lethality and growth retardation in mouse models, and is applicable to research related to Prader-Willi syndrome.
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