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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
SPNS2
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "SPNS2" in MCE Product Catalog:
4
4 Cited Publications
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Research Areas:
SLF1081851 is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 plays a key role in development and immune system [2].
1
1 Cited Publications
Cat. No.: HY-162655
CAS No.: 2764877-61-2
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SLF80821178 is a potent and orally active inhibitor of Sphingosine-1-Phosphate Transporter (Spns2). SLF80821178 inhibits S1P release with an IC50 of 51 nM in HeLa cells and a T1/2 of 2.4 h in mouse .
1
1 Cited Publications
Cat. No.: HY-150254A
Purity: 99.91%
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Research Areas:
SLB1122168 formic is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 formic inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC50 of 94 nM. SLB1122168 formic induces lymphopenia in circulating lymphocytes in mice and rats .
Cat. No.: HY-RS13691
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SPNS2 Human Pre-designed siRNA Set A contains three designed siRNAs for SPNS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156408
CAS No.: 3049214-20-9
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Spns2-IN-1 is a potent inhibitor of Spns2-dependent S1P transport (Spns2), with IC50 of 1.4±0.3 μM that plays an important role in immune response .
Cat. No.: HY-RS19483
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Spns2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Spns2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25976
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Research Areas:
Spns2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Spns2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-150254
CAS No.: 2999629-17-1
Target:
Research Areas:
SLB1122168 is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC50 of 94 nM. SLB1122168 induces lymphopenia in circulating lymphocytes in mice and rats .
Cat. No.: HY-149004B
CAS No.: 2999629-35-3
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SLF1081851 (hydrochloride) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (hydrochloride) plays a key role in the development and immune system .
Cat. No.: HY-149004A
CAS No.: 2763730-98-7
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SLF1081851 (TFA) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (TFA) plays a key role in development and immune system [2].
Cat. No.: HY-176500
CAS No.: 3035022-30-8
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Sphingolipid E is a synthetic pseudoceramide sphingolipid similar to type 2 ceramide with a metastable lamellar structure. Sphingolipid E ??can be used as a potential drug carrier to control the penetration of molecules as a lipid component of the intercellular space of the stratum corneum .
Cat. No.: HY-162655A
CAS No.: 2764877-62-3
Target:
Research Areas:
SLF80821178 hydrochloride is an orally active inhibitor for sphingosine-1-phosphate transporter (Spns2), that inhibits the sphingosine-1-phosphate (S1P) release in HeLa with an IC50 of 51 nM. SLF80821178 hydrochloride reduces the circulating lymphocyte without affecting plasma S1P levels in mice .
Cat. No.: HY-182375A
CAS No.: 2764877-95-2
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Research Areas:
SLB1122168 free base is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 free base inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC50 of 94 nM. SLB1122168 free base induces lymphopenia in circulating lymphocytes in mice and rats .
Cat. No.: HY-182375
CAS No.: 2764877-97-4
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(R)-SLB1122168 free base, an isomer of SLB1122168 free base (HY-182375A), is a spinster homolog 2 (SPNS2) inhibitor with an IC50 ≤2 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
