2763730-98-7
2763730-98-7
Chemical Structure
SLF1081851 TFA
- CAS No.: 2763730-98-7
- Formula:C23H34F3N3O3
- Molecular Weight:457.53
IUPAC Name: 3-(3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl)propan-1-amine 2,2,2-trifluoroacetate
InChIKey: KSPAYUOYCICAHW-UHFFFAOYSA-N
SMILES: NCCCC1=NC(C2=CC=C(CCCCCCCCCC)C=C2)=NO1.O=C(O)C(F)(F)F
Biological Activity: SLF1081851 (TFA) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (TFA) plays a key role in development and immune system[1][2].
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SLF1081851 TFA | SLF1081851 (TFA) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (TFA) plays a key role in development and immune system. | |||||||||||||||||||||
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References
- [1]. Fritzemeier R, et al. Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors. J Med Chem. 2022 Jun 9;65(11):7656-7681. [Content Brief]
- [2]. Lynch Kevin R, et al. Preparation of oxadiazoles as inhibitors of spinster homolog 2 (SPNS2) for use in therapy: World Intellectual Property Organization, WO2022056042[P]. 2022-03-17.
Keywords
