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Cat. No.: HY-156408

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Spns2-IN-1

Spns2-IN-1 is a potent inhibitor of Spns2-dependent S1P transport (Spns2), with IC₅₀ of 1.4±0.3 μM that plays an important role in immune response.

For research use only. We do not sell to patients.

CAS No.: 3049214-20-9
Formula: C₂₄H₄₀ClN₃
Molecular Weight:406.05

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Spns2-IN-1 Chemical Structure

CAS No.: 3049214-20-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Spns2-IN-1 is a potent inhibitor of Spns2-dependent S1P transport (Spns2), with IC₅₀ of 1.4±0.3 μM that plays an important role in immune response^[1].

IC₅₀ & Target

1.4±0.3 μM (Spns2-dependent S1P transport)^[1]

All LPL Receptor Isoforms :

Chemical Information

CAS No. 3049214-20-9
Molecular Weight 406.05
Formula C₂₄H₄₀ClN₃
SMILES

CCN1C(CCCN)=NC(C2=CC=C(CCCCCCCCCC)C=C2)=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Christopher W Shrader, et al. Imidazole-based sphingosine-1-phosphate transporter Spns2 inhibitors. Bioorg Med Chem Lett. 2023 Oct 11:96:129516. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Spns2-IN-1

All LPL Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Spns2-IN-1 Related Classifications

HY-156408 Related Classifications