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Cat. No.: HY-162655A

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SLF80821178 hydrochloride

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

SLF80821178 hydrochloride is an orally active inhibitor for sphingosine-1-phosphate transporter (Spns2), that inhibits the sphingosine-1-phosphate (S1P) release in HeLa with an IC₅₀ of 51 nM. SLF80821178 hydrochloride reduces the circulating lymphocyte without affecting plasma S1P levels in mice.

For research use only. We do not sell to patients.

CAS No.: 2764877-62-3
Formula: C₂₁H₃₆ClN₃O
Molecular Weight:381.98

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

SLF80821178 hydrochloride Chemical Structure

CAS No.: 2764877-62-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

All LPL Receptor Isoforms :

Chemical Information

CAS No. 2764877-62-3
Molecular Weight 381.98
Formula C₂₁H₃₆ClN₃O
SMILES

O=C(N1CCNCC1)NC2=CC=C(CCCCCCCCCC)C=C2.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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PLoS Pathog

A Spinster-like Transporter at the Inner Membrane Complex is critical for Toxoplasma gondii cytokinesis, motility and invasion. [Abstract]

2026 Jan 28;22(1):e1013886. PMID: 41604433

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Foster DJ, et al., Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. J Med Chem. 2024 Jul 11;67(13):11273-11295. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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SLF80821178 hydrochloride

1 Cited Publications

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Publications (1)
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SLF80821178 hydrochloride

Publications Citing Use of MedChemExpress (MCE) SLF80821178 hydrochloride

All LPL Receptor Isoforms

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

SLF80821178 hydrochloride Related Classifications

HY-162655A Related Classifications