country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-149004B

Copy Link Print Information

SLF1081851 hydrochloride

4 Cited Publications

Customer Review

Based on 4 publication(s) in Google Scholar

SLF1081851 (hydrochloride) is a Spns2 inhibitor, inhibits S1P release (IC₅₀=1.93 μM). SLF1081851 (hydrochloride) plays a key role in the development and immune system.

For research use only. We do not sell to patients.

CAS No.: 2999629-35-3
Formula: C₂₁H₃₄ClN₃O
Molecular Weight:379.97

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

SLF1081851 hydrochloride Chemical Structure

CAS No.: 2999629-35-3

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

SLF1081851 (hydrochloride) is a Spns2 inhibitor, inhibits S1P release (IC₅₀=1.93 μM). SLF1081851 (hydrochloride) plays a key role in the development and immune system^[1].

All LPL Receptor Isoforms :

Chemical Information

CAS No. 2999629-35-3
Molecular Weight 379.97
Formula C₂₁H₃₄ClN₃O
SMILES

NCCCC1=NC(C2=CC=C(CCCCCCCCCC)C=C2)=NO1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (4)

All

Sort by:

Journal Impact Factor

Cell

Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. [Abstract]

2023 Jun 8;186(12):2644-2655.e16. PMID: 37224812
Cell Commun Signal

Spinster homolog 2/S1P signaling ameliorates macrophage inflammatory response to bacterial infections by balancing PGE2 production. [Abstract]

2024 Sep 30;22(1):463. PMID: 39350143
Int Immunopharmacol

Liquiritigenin attenuates alcohol-induced liver inflammation by regulating the SphK1/S1P/SPNS2 signaling pathway. [Abstract]

2026 Jan 1;168(Pt 2):115881. PMID: 41297343
Pflugers Arch

Sphingosine kinase 1 inhibition aggravates vascular smooth muscle cell calcification. [Abstract]

2025 Jun;477(6):815-826. PMID: 39899071

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Russell Fritzemeier, et al. Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors. J Med Chem. 2022, 65, 11. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

SLF1081851 hydrochloride

4 Cited Publications

100 mg Get Quote

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Publications (4)
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

SLF1081851 hydrochloride

Publications Citing Use of MedChemExpress (MCE) SLF1081851 hydrochloride

All LPL Receptor Isoforms

Biological Activity

Chemical Information

Publications (4)

Purity & Documentation

References

Calculators

Help & FAQs

SLF1081851 hydrochloride Related Classifications

HY-149004B Related Classifications