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Staphylococci

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77

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9

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0925
    Oxacillin sodium salt
    Maximum Cited Publications
    14 Publications Verification

    Bacterial Antibiotic Infection
    Oxacillin sodium salt is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens .
    Oxacillin sodium salt
  • HY-112579
    Ceftobiprole
    3 Publications Verification

    Ro 63-9141; BAL 9141

    Bacterial Antibiotic Infection Inflammation/Immunology
    Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC90 value of 2 μg/mL for MRSA. Ceftobiprole also inhibits gram-positive and gram-negative pathogens. Ceftobiprole can be used for the study of hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia .
    Ceftobiprole
  • HY-B0269
    Rifapentine
    1 Publications Verification

    DL 473; Cyclopentylrifampicin

    Antibiotic Bacterial Infection
    Rifapentine (DL 473) is an antibiotic used in tuberculosis research .
    Rifapentine
  • HY-B1050

    SB-265805S; LB-20304a

    Bacterial Antibiotic DNA/RNA Synthesis Topoisomerase Infection
    Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections .
    Gemifloxacin mesylate
  • HY-146331

    Bacterial Infection
    PC190723 is a bacterial cell division protein FtsZ inhibitor (IC50 = 55 nM). PC 190723 prevents cell division. PC190723 has potent and selective bactericidal activity against staphylococci, including methicillin- and multi-drug-resistant Staphylococcus aureus. PC190723 induces nucleated assembly of Bs-FtsZ into single-stranded coiled protofilaments and polymorphic condensates. PC190723 can be studied in anti-bacterial infection research .
    PC190723
  • HY-106574A

    BAL5788 sodium

    Bacterial Infection Inflammation/Immunology
    Ceftobiprole medocaril (BAL5788) sodium is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .
    Ceftobiprole medocaril sodium
  • HY-B0465
    Oxacillin sodium monohydrate
    Maximum Cited Publications
    14 Publications Verification

    Bacterial Antibiotic Infection
    Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study .
    Oxacillin sodium monohydrate
  • HY-B1407
    Phthalylsulfathiazole
    2 Publications Verification

    N4-Phthalylsulfathiazole

    Antibiotic Bacterial Infection
    Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is an orally active sulfonamide intestinal antibacterial agent. Phthalylsulfathiazole has low toxicity and excellent bacteriostatic efficacy. Phthalylsulfathiazole inhibits E. coli, streptococci, staphylococci, and total fecal bacteria. Phthalylsulfathiazole can be used in research related to intestinal infections such as colon infection, bacillary dysentery, and ulcerative colitis .
    Phthalylsulfathiazole
  • HY-109000

    Debio 1450; AFN-1720

    Bacterial Infection
    Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
    Afabicin
  • HY-N6665

    Antibiotic Bacterial Infection
    Cefquinome sulfate is a broad-spectrum cephem antibiotic that has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, including Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae .
    Cefquinome sulfate
  • HY-N7101

    U-76,252; CS-807

    Bacterial Antibiotic Penicillin-binding protein (PBP) Infection
    Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .
    Cefpodoxime Proxetil
  • HY-10393

    PNU-100592

    Bacterial Antibiotic Infection
    Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of chloramphenicol (HY-B0239) and lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC90 for Staphylococcus aureus and Enterococcus is 1-4 μg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis .
    Eperezolid
  • HY-B1252

    Antibiotic Bacterial Infection Inflammation/Immunology
    Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
    Cefalonium
  • HY-14956
    Nemonoxacin
    1 Publications Verification

    TG-873870

    Antibiotic Bacterial Infection Inflammation/Immunology
    Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia .
    Nemonoxacin
  • HY-B1043

    Bacterial Antibiotic Infection
    Piromidic acid is an antibacterial agent. Piromidic acid is active against gramnegative bacteria and staphylococci and can be used for the research of intestinal, urinary, and biliary tract infections .
    Piromidic acid
  • HY-W141916

    Tetraglycylglycine; Gly-Gly-Gly-Gly-Gly; NSC 96353

    Amino Acid Derivatives Bacterial Infection
    Pentaglycine (Tetraglycylglycine; NSC 96353) is a bridging structure composed of five glycine residues. Pentaglycine serves as a characteristic peptidoglycan cross-bridge component of staphylococci and a specific substrate for lysostaphin. Pentaglycine maintains the integrity of the peptidoglycan cell wall of Staphylococcus aureus via peptide chain cross-linking and regulates bacterial growth. Pentaglycine expression is downregulated in high-glucose environments, inhibiting bacterial proliferation. Pentaglycine can be applied to studies related to Staphylococcus aureus infection .
    Pentaglycine
  • HY-B0925A

    Bacterial Antibiotic Infection
    Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens .
    Oxacillin
  • HY-125919

    Reactive Oxygen Species (ROS) Bacterial Endogenous Metabolite Infection Inflammation/Immunology
    Vulpinic acid, a lichen metabolite, decreases H2O2-induced ROS production, oxidative stress and oxidative stress-related damages in human umbilical vein endothelial cells (HUVEC). Vulpinic acid is active against staphylococci, enterococci, and anaerobic bacteria.Vulpinic acid has the potential for atherosclerosis research .
    Vulpinic acid
  • HY-121473

    Antibiotic Bacterial Fungal Parasite Infection
    Aklavin is a structural analog of Aclacinomycin A (HY-N2306) produced by Streptomyces strain A 1165. Aklavin possesses Z-DNA-inducing and stabilizing activities, along with antibiotic, anti-phage and broad-spectrum antimicrobial activities. Aklavin inhibits the proliferation of various viruses (such as influenza virus and poliovirus) and interferes with their nucleoprotein synthesis, while also exhibiting inhibitory effects on staphylococci, mycobacteria and specific fungi. Aklavin blocks phage-induced bacterial lysis by regulating host-parasite interactions. Aklavin shows specific toxicity to fertilized eggs and mice, and does not alter the splicing of the SMN2 gene .
    Aklavin
  • HY-N6665A

    Antibiotic Bacterial Infection
    Cefquinome is a broad-spectrum cephem antibiotic that has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, including Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae .
    Cefquinome
  • HY-B0269R

    DL 473 (Standard); Cyclopentylrifampicin (Standard)

    Reference Standards Antibiotic Bacterial Infection
    Rifapentine (Standard) is the analytical standard of Rifapentine. This product is intended for research and analytical applications. Rifapentine (DL 473) is an antibiotic used in tuberculosis research .
    Rifapentine (Standard)
  • HY-131989

    Deacetylcephapirin sodium

    Bacterial Infection
    Desacetylcephapirin (Deacetylcephapirin) sodium is an active metabolite of Cephapirin (HY-A0153A). Desacetylcephapirin sodium has antimicrobial against S. aureus and coagulase-negative staphylococci mastitis pathogen .
    Desacetylcephapirin sodium
  • HY-135184

    CBR-2092; TNP-2092

    Antibiotic Bacterial DNA/RNA Synthesis Infection
    Rifaquizinone (CBR-2092) is a Rifamycin-Quinolone Hybrid Antibiotic. Rifaquizinone inhibits wild-type S. aureus RNA polymerase with an IC50 of 34 nM. Rifaquizinone is effective against S. aureus infections, with MICs ranged from 0.008 to 0.5 μg/mL for 300 clinical isolates of staphylococci and streptococci .
    Rifaquizinone
  • HY-14956S

    TG-873870-d3

    Bacterial Inflammation/Immunology
    Nemonoxacin-d3 is the deuterium labeled Nemonoxacin. Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia .
    Nemonoxacin-d3
  • HY-139805

    Antibiotic Bacterial Infection
    Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research .
    Ticarcillin
  • HY-148209

    Antibiotic Bacterial Infection
    Balhimycin is a glycopeptide antibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes .
    Balhimycin
  • HY-116039

    Ro11-8958

    Dihydrofolate reductase (DHFR) Bacterial Infection
    Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor. Epiroprim displays excellent activity against staphylococci, enterococci, pneumococci, and streptococci .
    Epiroprim
  • HY-B1252A

    Antibiotic Bacterial Infection Inflammation/Immunology
    Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
    Cefalonium hydrate
  • HY-106574

    BAL5788

    Bacterial Infection Inflammation/Immunology
    Ceftobiprole medocaril (BAL5788) is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .
    Ceftobiprole medocaril
  • HY-135196

    MDL 62873

    Bacterial Drug Derivative Infection
    Mideplanin (MDL 62873) is an antimicrobial agent, semisynthetic amide derivative of Teicoplanin (HY-A0097). Mideplanin is highly active in vitro against staphylococci .
    Mideplanin
  • HY-100997R

    A82846B (Standard); LY 264826 (Standard); PA 45052A (Standard)

    Reference Standards Antibiotic Bacterial Infection
    Chloroorienticin A (Standard) is the analytical standard of Chloroorienticin A (HY-100997). This product is intended for research and analytical applications. Chloroorienticin A (A82846B) is a glycopeptide antibiotic. Chloroorienticin A exhibits excellent activity against staphylococci and streptococci .
    Chloroorienticin A (Standard)
  • HY-N6665R

    Reference Standards Antibiotic Bacterial Infection
    Cefquinome (sulfate) (Standard) is the analytical standard of Cefquinome (sulfate). This product is intended for research and analytical applications. Cefquinome sulfate is a broad-spectrum cephem antibiotic that has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, including Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae .
    Cefquinome sulfate (Standard)
  • HY-117845

    LL-E19085α

    Antibiotic Bacterial Infection
    Citreamicin alpha (LL-E 19085-alpha) is an antibiotic whose in vitro antimicrobial activity against 429 clinical isolates of Gram-positive cocci has been tested by the agar dilution method. These microorganisms included 313 strains of Staphylococci and 116 strains of Streptococci. The in vitro activity of Citreamicin alpha was compared with that of ampicillin, amoxicillin, ceftriaxone, erythromycin, and vancomycin. For Staphylococci, the MIC values of Citreamicin alpha ranged from 0.12-4.0 μg/ml, and for Streptococcus pyogenes of the genus Streptococcus, it was 0.03-0.12 μg/ml. However, enterococci were relatively resistant, requiring 2.0 μg/ml of the agent to inhibit 64% of the 62 tested strains. The in vitro activity of this antibiotic was much better than that of ampicillin, amoxicillin, ceftriaxone, and erythromycin, but comparable or slightly inferior to that of vancomycin.
    Citreamicin alpha
  • HY-130337

    Antibiotic Bacterial Infection
    Teicoplanin A2-2 is a glycopeptide antibiotic. Teicoplanin A2-2 exhibits antibacterial activity, particularly against coagulase-negative staphylococci (CNS). Teicoplanin A2-2 inhibits bacterial cell wall synthesis by competitively binding to the terminal D-Ala-D-Ala peptide bonds in the cell wall synthesis process, leading to bacterial death. Teicoplanin A2-2 can be used for research into bacterial resistance mechanisms and the development of new antibiotics .
    Teicoplanin A2-2
  • HY-121195

    PC-904

    Bacterial Infection
    Apalcillin (PC-904) in combination with Ro 48-1220, a penam sulfone β-lactamase inhibitor, demonstrated broad-spectrum activity against gram-negative aerobic and anaerobic bacteria, excluding Klebsiella oxytoca. It exhibited potent activity against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with effective MICs (11 μg/mL). The combination also inhibited Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter species at low MICs (0.25 to 4 μg/mL). However, its efficacy against oxacillin-resistant staphylococci and certain gram-positive organisms was limited. Apalcillin/Ro 48-1220 showed comparable efficacy to piperacillin/tazobactam against some extended-spectrum β-lactamase-producing Escherichia coli but was less effective against SHV-type β-lactamases .
    Apalcillin
  • HY-100997

    A82846B; LY 264826; PA 45052A

    Antibiotic Bacterial Infection
    Chloroorienticin A (A82846B) is a glycopeptide antibiotic. Chloroorienticin A exhibits excellent activity against staphylococci and streptococci .
    Chloroorienticin A
  • HY-129435

    Antibiotic Bacterial Infection Cancer
    Altromycin E is an antibiotic, that exhibits antibacterial against Streptococci and Staphylococci with MIC of 0.2-3.12 μg/mL. Altromycin E can be used in anti-tumor research .
    Altromycin E
  • HY-109000A

    Debio 1450 disodium; AFN-1720 disodium

    Bacterial Infection
    Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci .
    Afabicin disodium
  • HY-113602

    Antibiotic 273 A1-beta

    Antibiotic Bacterial Infection
    Paldimycin B (Antibiotic 273 A1-beta) is a powerful semi-synthetic antibiotic with antibacterial activity against S. aureus and coagulase-negative staphylococci .
    Paldimycin B
  • HY-B0925R

    Reference Standards Bacterial Antibiotic Infection
    Oxacillin (sodium salt) (Standard) is the analytical standard of Oxacillin (sodium salt). This product is intended for research and analytical applications. Oxacillin sodium salt is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens .
    Oxacillin sodium salt (Standard)
  • HY-121474

    SF-2052

    Antibiotic Bacterial Infection
    Dactimicin is a pseudodisaccharide aminoglycoside. Dactimicin is an antibiotic that can inhibit the growth of methicillin-susceptible S. aureus isolates and coagulase-negative staphylococci with MIC50s of 2 μg/mL. Dactimicin is active against organisms possessing aminoglycoside-modifying enzymes .
    Dactimicin
  • HY-B1252R

    Reference Standards Antibiotic Bacterial Infection Inflammation/Immunology
    Cefalonium (Standard) is the analytical standard of Cefalonium. This product is intended for research and analytical applications. Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
    Cefalonium (Standard)
  • HY-B1252AS

    Isotope-Labeled Compounds Infection
    Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
    Cefalonium-d4 hydrate
  • HY-B1050R

    SB-265805S (Standard); LB-20304a (Standard)

    Reference Standards Bacterial Antibiotic DNA/RNA Synthesis Topoisomerase Infection
    Gemifloxacin (mesylate) (Standard) is the analytical standard of Gemifloxacin (mesylate). This product is intended for research and analytical applications. Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections .
    Gemifloxacin mesylate (Standard)
  • HY-107075A

    Bacterial Infection
    WCK-1152 is a fluoroquinolone antibacterial agent. WCK-1152 is active against resistant pathogens bearing mutations of DNA gyrase and/or topoisomerase IV which also express efflux pumps. WCK-1152 can be used for the research of infection, such as respiratory infections caused by resistant pneumococci and staphylococci .
    WCK-1152
  • HY-B1148A
    Furaltadone
    1 Publications Verification

    Altafur

    Bacterial Infection
    Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
    Furaltadone
  • HY-U00255

    Bacterial Infection
    BO3482 has Antimicrobial activity and can inhibit the growth of methicillin-resistant Staphylococci (MRS) with an MIC90 of 6.25 mg/mL.
    BO3482
  • HY-B0465R

    Reference Standards Bacterial Antibiotic Infection
    Oxacillin (sodium monohydrate) (Standard) is the analytical standard of Oxacillin (sodium monohydrate). This product is intended for research and analytical applications. Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study .
    Oxacillin sodium monohydrate (Standard)
  • HY-B1148B

    Altafur L-tartrate

    Bacterial Infection Inflammation/Immunology
    Furaltadone L-tartrate (Altafur L-tartrate), a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
    Furaltadone L-tartrate
  • HY-B0925AS

    Bacterial Antibiotic Infection
    Oxacillin-d5 is the deuterium labeled Oxacillin . Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens .
    Oxacillin-d5

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