85-73-4
Chemical Structure
Phthalylsulfathiazole
Synonym(s): N4-Phthalylsulfathiazole
- CAS No.: 85-73-4
- Formula:C17H13N3O5S2
- Molecular Weight:403.43
IUPAC Name: 2-((4-(N-(thiazol-2-yl)sulfamoyl)phenyl)carbamoyl)benzoic acid
InChIKey: PBMSWVPMRUJMPE-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC=C1C(NC2=CC=C(S(=O)(NC3=NC=CS3)=O)C=C2)=O
Biological Activity: Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is an orally active sulfonamide intestinal antibacterial agent. Phthalylsulfathiazole has low toxicity and excellent bacteriostatic efficacy. Phthalylsulfathiazole inhibits E. coli, streptococci, staphylococci, and total fecal bacteria. Phthalylsulfathiazole can be used in research related to intestinal infections such as colon infection, bacillary dysentery, and ulcerative colitis[1][2].
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Phthalylsulfathiazole | 95.0% | Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is an orally active sulfonamide intestinal antibacterial agent. Phthalylsulfathiazole has low toxicity and excellent bacteriostatic efficacy. Phthalylsulfathiazole inhibits E. coli, streptococci, staphylococci, and total fecal bacteria. Phthalylsulfathiazole can be used in research related to intestinal infections such as colon infection, bacillary dysentery, and ulcerative colitis. | ||||||||||||||||||||
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Phthalylsulfathiazole (Standard) | ≥98% | Phthalylsulfathiazole (N4-Phthalylsulfathiazole) Standard is the analytical standard of Phthalylsulfathiazole (HY-B1407). This product is intended for research and analytical applications. Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is an orally active sulfonamide intestinal antibacterial agent. Phthalylsulfathiazole has low toxicity and excellent bacteriostatic efficacy. Phthalylsulfathiazole inhibits E. coli, streptococci, staphylococci, and total fecal bacteria. Phthalylsulfathiazole can be used in research related to intestinal infections such as colon infection, bacillary dysentery, and ulcerative colitis. | ||||||||||||||||||||
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Similarity Score 0.71
HY-B0967Phthalylsulfacetamide -
Similarity Score 0.70
HY-123833PF-05661014 -
Similarity Score 0.66
HY-133933Maleylsulfathiazole -
Similarity Score 0.66
HY-B0921RSuccinylsulfathiazole (Standard) -
Similarity Score 0.65
HY-121585CAY10698 -
Similarity Score 0.64
HY-49066Sodium Channel inhibitor 4 -
Similarity Score 0.62
HY-16268Kartogenin -
Similarity Score 0.62
HY-16787ICA-121431 -
Similarity Score 0.60
HY-146474EGFR-IN-54 -
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References
- [1]. Miller A K. The effect of succinylsulfathiazole and phthalylsulfathiazole on the bacterial flora of rat feces. The Journal of Nutrition, 1945, 29(2): 143-154.
- [2]. STREICHER M H. PHTHALYLSULFATHIAZOLE (SULFATHALIDINE): CLINICAL, CHEMICAL AND BACTERIOLOGIC EVALUATIONS IN INFECTIOUS DISEASES OF THE COLON. Journal of the American Medical Association, 1945, 129(16): 1080-1083.
