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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
TAF1
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "TAF1" in MCE Product Catalog:
4
4 Cited Publications
Target:
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BAY-299, a chemical probe, is a very potent, dual inhibitor with IC50s of 67 nM for BRPF2 bromodomains (BD), 8 nM for TAF1 BD2, and 106 nM for TAF1L BD2.
2
2 Cited Publications
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CeMMEC13 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.
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CeMMEC1 is an inhibitor of BRD4, and also has high affinity for TAF1, with an IC50 of 0.9 μM for TAF1, and a Kd of 1.8 μM for TAF1 (2).
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GNE-375 is a potent and highly selective BRD9 inhibitor with an IC50 of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4, TAF1, and CECR2. GNE-375 decreases BRD9 binding to chromatin [1].
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UMB-32, a potent, selective BRD4 inhibitor, binds BRD4 with the Kd of 550 nM, and IC50 of 637 nM. UMB-32 also shows potency against TAF1, a bromodomain-containing transcription factor [1].
Cat. No.: HY-176467
CAS No.: 1926986-25-5
Research Areas:
TAF1 ligand 1 is a TAF1 ligand. TAF1 ligand 1 can be used as a Ligands for Target Protein for PROTAC synthesis, such as ZS3-046 (HY-176457) [1].
Cat. No.: HY-RS14157
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TAF1 Human Pre-designed siRNA Set A contains three designed siRNAs for TAF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17005
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Taf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Taf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-150239
CAS No.: 2097610-30-3
Synonyms: BAY-299N
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BAY-364 (BAY-299N) is an inhibitor of the second bromine domain in TAF1. BAY-364 inhibits the TAF1 of Kasumi-1 cells, CD34 + cells and K562 cells with IC50 values of 1.0 µM, 10.4 µM and 10.0 µM respectively [1].
Cat. No.: HY-RS23448
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Taf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Taf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176457
CAS No.: 3087879-97-5
Research Areas:
ZS3-046 is a TAF1 PROTAC degrader. ZS3-046 promotes the ubiquitination and degradation of TAF1. ZS3-046 activates p53 and induces apoptosis in acute myeloid leukemia (AML) cells. ZS3-046 has antitumor activity in an AML tumor xenograft mouse model [1].
Cat. No.: HY-111445A
CAS No.: 2095432-53-2
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CeMMEC1 (hydrochloride) is an N-methylisoquinolinone derivative that inhibit the second bromodomain of TAF1 with an IC50 of 0.9 μM.
Cat. No.: HY-78197
CAS No.: 832114-00-8
Cat. No.: HY-111445R
CAS No.: 440662-09-9
Research Areas:
CeMMEC1 (Standard) is the analytical standard of CeMMEC1 (HY-111445). This product is intended for research and analytical applications. CeMMEC1 is an inhibitor of BRD4, and also has high affinity for TAF1, with an IC50 of 0.9 μM for TAF1, and a Kd of 1.8 μM for TAF1 (2).
Cat. No.: HY-RS14163
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TAF1A Human Pre-designed siRNA Set A contains three designed siRNAs for TAF1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14166
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TAF1L Human Pre-designed siRNA Set A contains three designed siRNAs for TAF1L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14164
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TAF1C Human Pre-designed siRNA Set A contains three designed siRNAs for TAF1C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14165
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TAF1D Human Pre-designed siRNA Set A contains three designed siRNAs for TAF1D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
