2 Results for "

TEAD subtype

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "TEAD subtype" in MCE Product Catalog:

Cat. No.: HY-147208
CAS No.: 2738542-58-8
Purity:  99.87%
Target:  

YAP

Research Areas:  

Cancer

MSC-4106 is an orally active and potent inhibitor of YAP/TAZ-TEAD. MSC-4106 inhibits TEAD1 or TEAD3 auto-palmitoylation and shows inhibitory effect on NCI-H226 tumor xenograft model .
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Cat. No.: HY-147209
Target:  

YAP

Research Areas:  

Metabolic Disease

DC-TEAD3in03 is a subtype-selective and covalent TEAD3 inhibitor with an IC50 of 0.16 μM. DC-TEAD3in03 exhibits the inhibitory activity on TEAD1/2/4 reduced by more than 100 times. DC-TEAD3in03 has the IC50 for TEAD3 of 1.15 μM in the GAL4-TEAD reporter gene experiment in cells, and it does not interfere with the β-catenin pathway. DC-TEAD3in03 reduces the growth rate of the zebrafish tail fin. DC-TEAD3in03 can be used to study the proportional growth of appendages in vertebrates .
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